SPT Labtech Japan Official site

Advancing medicinal chemistry with high-throughput low-volume liquid handling

SPT Labtech Japan

Developing pharmaceutical compounds with improved efficacy and specificity profiles means manipulating small molecules at the nanoscale. Since the structure of a molecule determines its function, approaches that provide access to diverse molecular structures are extremely important. Advances in computational methods and automation have significantly enhanced the ability of medicinal chemists to explore vast chemical spaces and validate novel compounds on a large scale. For example, by integrating virtual screening with high-throughput experiments, scientists can prioritize, validate, and optimize promising candidate compounds repeatedly, thereby shortening the timelines for drug discovery and development. This webinar will explore how automation, particularly low-volume liquid handling, promotes throughput in medicinal chemistry by increasing the number of data points generated for each nanoscale experiment. It will also discuss volumetric technology that enables the precise handling of ultra-small, difficult-to-manage liquids, overcoming reproducibility challenges. Case studies from leading research institutions will showcase how these technologies are successfully driving advancements in science.