SPT Labtech Japan Official site

Webinar Announcement: Automating antibiotic discovery in academia: A collaborative screening effort to identify novel TB therapeutics

SPT Labtech Japan

- Screening of tuberculosis treatment drugs using the latest automation technology - Identification of promising enzyme inhibitors through the evaluation of 6,000 compounds - Confirmation of the effectiveness of automation systems in streamlining the drug discovery process - Contribution to the development of new treatment methods for drug-resistant tuberculosis In research aimed at the novel development of tuberculosis treatment drugs, a collaborative study was conducted by SPT Labtech, Automata, GSK, and the Francis Crick Institute. Utilizing the latest automation technology, large-scale screening targeting key metabolic pathways of the tuberculosis bacterium was carried out. In particular, the efficacy, selectivity, and microbiological effectiveness of 6,000 compounds were evaluated. This initiative accelerated the identification of promising enzyme inhibitors and established a foundation for further drug discovery chemistry research. Additionally, important insights were gained regarding the potential integration of robotic platforms in high-throughput drug discovery through improvements in the automated workflow. This research represents a significant step in the development of new treatment methods in response to the increasing challenge of drug-resistant tuberculosis.