Nanoliter dispensing system mosquito HTS
For dispensing applications of several hundred nL!
The "mosquito HTS" is a robust nanoliter-scale dispensing device that employs a positive displacement method. It not only allows for precise aspiration and dispensing but also enables accurate mixing, making it suitable for various applications. By minimizing the sample volume in sample management workflows and genomics research, it contributes to cost reduction. ● Cost reduction through miniaturization and low dead volume With its accurate dispensing mechanism, it handles precious samples and expensive reagents in small volumes while minimizing dead volume, significantly reducing running costs. ● Reduced hands-on time and improved reproducibility through automation With rapid and precise operation, it eliminates dispensing errors and cross-contamination caused by human error, enhancing reproducibility. ● Improved data reliability through increased sample size The benefits of miniaturization extend beyond mere cost savings; it allows for multiple experiments to be conducted in parallel, thereby enhancing data reliability. ● User-friendly The easy-to-use software makes the protocol creation process very simple.
basic information
■ Number of channels: 8 / 16 channels or single channel ■ Dispensing capacity: 25 - 1200 nL (LV model), 500 nL - 5 µL (HV model) ■ Compatible wells: 96, 384, 1536 well SBS plates ■ Dispensing accuracy (CV value) for LV model: < 8% (50 nL), < 7% (100 nL) ■ Dispensing accuracy (CV value) for HV model: < 3% (1000 nL) ■ Number of plates: 2 or 5 ■ Main unit size (mm): W390 or W790 x D470 x H690
Price information
Prices vary by model. Please feel free to contact us.
Price range
P7
Delivery Time
OTHER
The average delivery time is 2 to 3 months.
Model number/Brand name
HTS model
Applications/Examples of results
【HTS Field】 □ Creation of assay-ready plates □ Serial dilution □ Hit picking □ Plate copying in the nL range
Detailed information
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The chip adopts a positive displacement method, allowing for high-precision dispensing of not only high-viscosity and highly volatile solutions but also foamy solutions. It is made of stainless steel and HDPE, and can also dispense DMSO.
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Dispensing will be done by row on 8 channels or 16 channels. *The X1 model is designed for dispensing on a per channel basis and is specialized for applications such as hit picking.
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The protocol can be easily designed to match the wizard (currently only for Genomics HV, Xtal3, and LCP models). The HTS model includes a serial dilution wizard.
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[Option] Precision Humidification Chamber: In nano-liter scale micro-dispensing, the effects of drying cannot be ignored. The chamber surrounding the mosquito plate deck maintains an appropriate humidity environment.
Related Videos
Line up（4）
| Model number | overview |
|---|---|
| HTS HV | Capacity: 500-5000nL, Number of channels: 8 or 16 |
| HTS LV | Capacity: 25-1200nL, Number of channels: 8 or 16 |
| X1 HV | Capacity: 500-5000nL, Number of channels: 8 or 16 |
| X1 LV | Capacity: 25-1200nL, Number of channels: 8 or 16 |
catalog（1）
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News about this product（3）
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Accelerating chemical discovery through high-throughput experimentation: in conversation with Matthew Gaunt
Professor Matthew Gound of the University of Cambridge is advancing the development of chemical reactions that were previously impossible using traditional methods by utilizing high-throughput experimentation (HTE). HTE allows for the parallel execution of a large number of reactions, enabling the simultaneous examination of many variables such as catalysts, substrates, and additives. Using automated liquid dispensers like mosquito(R), precise reagent handling at the nanoliter scale is performed, accommodating reaction setups and analyses in 384 or 1536 well plates. The research subjects range widely, including photoredox catalysts, C–H activation, and nucleic acid (RNA, DNA) chemistry, allowing for efficient exploration even with small sample sizes. Additionally, analytical techniques such as UPLC-MS and high-throughput NMR enable the acquisition of quantitative and high-quality data. The flexible operation is also characterized by conducting reactions at the necessary scale using partially filled 1536 well plates. In the future, such high-quality data will be essential for predicting chemical reactions using AI and machine learning, highlighting the increasing importance of data science.
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Norwegian Sequencing Centre enhances multiomic workflows with automated liquid handling
The Norwegian Sequencing Centre (NSC), located at Oslo University Hospital, has recognized the importance of lab automation in fields such as proteomics and genomics through practical experience. Recently, they have implemented liquid handling solutions, including our firefly system, significantly improving workflows to address daily operations and high-throughput challenges. These automations have enhanced work efficiency, optimized reagent usage, and reduced the risk of errors. In NSC's automation efforts, the following factors were key selection criteria: - Cost - Efficiency - Usability - Service support Considering various other conditions, our system was adopted as the most suitable for the automated workflow. It is believed that the importance of automation will continue to grow, becoming an essential element for core facilities. NSC's initiatives are expected to serve as a reference for other research institutions and as a model for maximizing the benefits of automation. For detailed news, please refer to the articles linked.
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Webinar Announcement: Advanced Proteomic Biomarker Discovery for Understanding Disease Pathophysiology
Announcement of a webinar for researchers in the pharmaceutical and biotechnology industries, as well as academia, interested in proteomics and multi-omics. Title: "Advanced proteomic biomarker discovery for understanding disease pathophysiology" Speakers: Eric Schordan, PhD and Kamila Koprowska, PhD Overview: How large-scale proteomics data generation, integrating the Olink Explore platform and positive displacement liquid handling technology, provides deep insights into the pathophysiological mechanisms underlying various drugs and diseases, and how it offers a comprehensive reading of protein expression levels in biological samples.
