Five Tips for Successful Cleaning Validation

To successfully conduct cleaning validation, it is necessary to select the appropriate analytical method!

last updated May 26, 2025

Water Quality Monitoring at Oil Refineries: Utilizing Real-Time Data

The impact of real-time data on quality/compliance/reuse!

last updated May 26, 2025

Portable Residual Chlorine Meter MD50

Compact, lightweight, easy to operate, and high-performance handy residual chlorine meter.

last updated May 26, 2025

Cost comparison of TOC and HPLC for cleaning validation.

[Application Note] A cost comparison between TOC measurement and HPLC in cleaning validation was conducted!

last updated May 26, 2025

TOC-based lab/at-line/online cleaning validation

The Sievers TOC meter for cleaning validation is effective in various situations such as lab, at-line, and online, depending on the application.

last updated May 26, 2025

Cleaning validation: Verifying the performance of the cleaning process.

[Fact Sheet] Effectiveness of TOC in Each Phase of Cleaning Validation (Design, Validation, Verification)

last updated May 26, 2025

Swab recovery rate of the compound in the worst-case scenario (feasibility test)

[Application Note] Verification Method for Recovery Rates of TOC Method in Cases of Low Solubility Compounds or Improper Cleaning Processes

last updated May 26, 2025

Calculation of maximum allowable carryover in cleaning validation.

[Application Note] Calculation Method for Maximum Allowable Carryover (MAC) in Cleaning Validation

last updated May 26, 2025

Evaluation of the validity of cleaning standards based on engineering capability index.

[Application Note] A Method for Evaluating the Validity of Cleaning Standards Using Process Capability Indices

last updated May 26, 2025

TOC recovery rate of complex compounds: cleaning agents

[Application Note] This document introduces appropriate procedures for recovering complex compounds such as alkaline cleaning agents using TOC.

last updated May 26, 2025

Evaluation of the recovery rate of cleaning agents using the Sievers M9 TOC analyzer.

[Application Note] We measured trace residues of 12 types of cleaning agents using the Sievers M9 TOC analyzer.

last updated May 26, 2025

Real-time low-flow cleaning efficacy evaluation of pharmaceuticals using TOC and conductivity.

Application Note: Evaluation of Cleanability of Substances in Cleaning Processes Using TOC Analyzer

last updated May 26, 2025

Comparison of TOC Cleaning Validation Swab Kits

[Application Note] Selection of Swab Kits for Cleaning Validation

last updated May 26, 2025

TOC measurement of 0.2M sodium hydroxide using M9 type.

[Application Note] Detection of Sodium Hydroxide Using TOC and Conductivity

last updated May 26, 2025

TOC measurement of 0.2M potassium hydroxide using the M9 type.

Application Note: Detection of Potassium Hydroxide Using TOC and Conductivity

last updated May 26, 2025

Simultaneous measurement of TOC and conductivity to analyze non-conductive organic substances in cleaning agents.

[Application Note] A New Perspective on Cleaning Validation: Residual Assessment of Cleaning Agents through Simultaneous Measurement of TOC and Conductivity

last updated May 26, 2025

TOC recovery rate of insoluble compounds and refractory compounds.

[Application Note] TOC Measurement of Insoluble Compounds and Recalcitrant Compounds Related to the Biopharmaceutical, Pharmaceutical, and Cosmetics Industries

last updated May 26, 2025

Comparison of TOC measurements in the cleaning validation of protein samples.

The Sievers TOC analyzer can measure protein samples with high accuracy.

last updated May 26, 2025

TOC recovery rate of gluten using Sievers M9

[Application Note] Gluten Management in Food and Beverage Factories

last updated May 26, 2025

Cleaning evaluation: Microbial TOC recovery rate and linearity

[Application Note] Reducing Microbial Contamination Risks with TOC

last updated May 26, 2025

Online cleaning validation using TOC, IC, and conductivity.

Application Note: Optimization of Cleaning Conditions Using an Online TOC Analyzer

last updated May 26, 2025

Validation support package for cleaning validation.

[Application Note] Comprehensive Document for Building Cleaning Validation Using Sievers TOC Analyzer

last updated May 26, 2025

Detection of TOC and conductivity of alkaline cleaning agents using TOC measurement.

[Test Report] Simultaneous Measurement of TOC and Conductivity of Alkaline Cleaners Using Sievers M Series TOC Analyzer

last updated May 26, 2025

At-line TOC measurement for cleaning validation and product changeover.

[Application Note] Applying PAT to At-Line Cleaning Validation Using TOC

last updated May 26, 2025

Reducing cleaning validation and product changeover costs with inline TOC measurement.

[Case Study] Reduced cleaning validation and product changeover costs by 92% with Atline TOC measurement.

last updated May 26, 2025

Sievers TOC meter standard solution & TOC vials

Sievers standard solution and TOC vials compatible with various manufacturers' TOC analyzers.

last updated May 26, 2025

Online Sludge Interface Sensor IFL 700IQ

Supports continuous measurement using ultrasonic echo method.

last updated May 26, 2025

Portable Phosphate Meter MD50

Easy-to-use Lovibond turbidity meter.

last updated May 26, 2025

Portable Water Quality Meter SS Model MD50

Easy-to-use Lovibond photometer.

last updated May 26, 2025

Portable High-Concentration Residual Chlorine Meter MD50

Easy-to-use Lovibond colorimeter.

last updated May 26, 2025