Hydrophilic interaction chromatography
It is possible to strongly retain solutes! Beneficial not only for LC/MS but also for preparative chromatography.
This document explains Hydrophilic Interaction Liquid Chromatography (HILIC), which is a suitable separation method for highly polar hydrophilic compounds. It includes the basic theory of HILIC and notes on precautions when using the separation mode. Additionally, it introduces the zwitterionic ZIC-HILIC series from Merck SeQuant and describes application examples for various hydrophilic compounds. We encourage you to read it. [Contents (excerpt)] ■ Introduction ■ For first-time users of ZIC-HILIC ■ Why HILIC mode? ■ Equipment ■ Principle of separation *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Other Published Content (Excerpt)】 ■ Column Care ■ Mobile Phase ■ Injector ■ Sample Preparation Precautions ■ Features of the ZIC-HILIC Series *For more details, please refer to the PDF document or feel free to contact us.
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Applications/Examples of results
【Analysis Examples】 ■ Analysis of nucleotides, analysis of purines and pyrimidines ■ Analysis of cAMP, AMP, ADP, ATP, and high-speed analysis of AMP and ATP, etc. *For more details, please refer to the PDF materials or feel free to contact us.
