Dear Sir/Madam, I would like to express my congratulations on the continued prosperity of your company. I sincerely appreciate your exceptional patronage. As you may already be aware, there has been a recent global surge in the costs of raw materials and logistics, making it extremely difficult for our company to maintain the current price levels of our products. It is with great regret that I must inform you that we will be revising our prices effective April 1, 2026. The new prices for each product are as follows: - Antineoplastic Preparation Training Kit A (HUSMH-A-100CISN) Old Price (excluding tax): ¥24,100 New Price (excluding tax): ¥28,900 - Antineoplastic Preparation Training Kit B (HUSMH-B-100CISN) Old Price (excluding tax): ¥21,500 New Price (excluding tax): ¥25,800 We apologize for any inconvenience this may cause and kindly ask for your understanding. Sincerely,

Dear Sir/Madam, I would like to express my sincere congratulations on the continued prosperity of your company. I am deeply grateful for your exceptional patronage. As you may already be aware, there has been a recent global surge in raw material and logistics costs, making it extremely difficult for our company to maintain the current price levels of our products. It is with great regret that I must inform you that we will be revising our prices effective April 1, 2026. The new prices for our products are as follows: New price list for each product: - Kemoclean Special Spray (PCN-SPR) Old price (excluding tax): ¥2,700 New price (excluding tax): ¥3,200 We apologize for any inconvenience this may cause and kindly ask for your understanding. Sincerely,

Dear Sir/Madam, Thank you very much for your continued support of our products. Recently, due to the significant rise in raw material costs, as well as increases in logistics and labor costs, we have made every effort to maintain our prices through corporate initiatives. However, it has become extremely difficult to sustain our product prices. Therefore, it is with great regret that we must implement a price revision for the affected products. We sincerely apologize to our valued customers and kindly ask for your understanding of the circumstances. We hope you will continue to support our products in the future. Sincerely, Start Date for Price and Specification Revisions: Orders received from April 1, 2026. Please check the PDF file for details on the affected products.

■□─━─━─━─━─━─━─━─━─━─━─━─━─━─━─━─□■ Infection Prevention Clean Bed NB-1200S An ideal simple negative pressure booth for air infection prevention measures! Easy to install! ■□─━─━─━─━─━─━─━─━─━─━─━─━─━─━─━─□■ 【Features】 ○ Maintains negative pressure inside the unit, preventing contaminated air from leaking outside ○ Wide suction surface quickly draws in contaminated air ○ Uses HEPA filters in the exhaust system ○ The main body features an antibacterial coating ○ Uses transparent vinyl curtains that do not create a sense of pressure ○ Quiet operating sound

■□─━─━─━─━─━─━─━─━─━─━─━─━─━─━─━─□■ Class 2 Cabinet for Biohazard Countermeasures Fatigue-resistant! Allows for long hours of operation with a natural posture! ■□─━─━─━─━─━─━─━─━─━─━─━─━─━─━─━─□■ When handling pathogens and similar materials, it is essential to ensure the safety of the operator and to handle materials in a sterile environment. This necessitates the confinement of contaminating aerosols that inevitably arise within the work area. For tasks that require clean air in such work areas, a Class 2 cabinet is used. The Class 2 cabinet prevents the escape of contaminating aerosols through the inflow airflow from the front opening and supplies clean air, processed through a HEPA filter, in a unidirectional flow to the work area, keeping the workspace clean. Additionally, exhaust air is released outside the cabinet after being processed by a HEPA filter. 【Features】 ■ Allows for long hours of operation with a fatigue-resistant and natural posture ■ Standard equipped with an anemometer and operation totalizer ■ Automatic shut-off time setting for sterilization lamps is possible ■ Interlock mechanism adopted ■ Inspections and maintenance of HEPA filters, etc., are carried out by qualified personnel