Real-time interactive site metrology "heliXcyto"
A new measurement method that enables real-time interaction analysis on cells!
"heliXcyto" enables the automatic analysis of binding constants (affinity, avidity) while maintaining the complexity of biological systems by directly measuring the kinetics of molecular binding and dissociation on the cell surface. The newly designed cellTRAP biochip, equipped with a cage made of biocompatible polymer, allows for the capture of various types of single cells on the chip and enables real-time interaction measurement (RT-IC) on the cell surface. 【Features】 ■ Fully automated workflow ■ Compatible with various cells (live cells and fixed cells) ■ Supports various complex media ■ Analysis of single cells and multiple cells ■ Analysis at low membrane protein expression levels ■ Ultra-high sensitivity fluorescence detection *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Workflow】 1. Create a dilution series of fluorescently labeled analite. 2. Harvest the cells. 3. Set the samples in the auto-sampler and start the assay. *For more details, please refer to the PDF document or feel free to contact us.
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Applications/Examples of results
【Applications】 ■Biopharmaceutical development ■Cell therapy ■Biophysical analysis of cell surface receptors (such as GPCRs) *For more details, please refer to the PDF document or feel free to contact us.
