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We would like to express our sincere gratitude for your continued support. We are pleased to announce that we will be holding the "Gattefosse Scientific Seminar 2026," which has been well-received every year, once again this year. Gattefosse is a French manufacturer of functional lipid additives with a long history. We provide lipid-based additives used for a wide range of purposes, including improving the solubility of poorly soluble active pharmaceutical ingredients, enhancing bioavailability, and improving absorption. In this seminar, in addition to presentations by Gattefosse engineers, we will welcome external speakers to deliver practical content on cutting-edge market trends and technical insights. This time, you can participate both in person and via WEB (live streaming).

We will be showcasing functional lipid-based additives, new solid dispersion carriers, and release control additives utilizing cellulose derivatives at "CPHI Japan 2026." All of these are unique additives with high functionality, actively used in a wide range of fields such as oral, transdermal, and suppository applications. We have prepared numerous solutions that directly address the challenges of formulation design. We sincerely look forward to your visit. 【Exhibition Details (Partial)】 ◆Eastman Chemical (USA) - Enteric coatings, amorphous solid dispersion polymers - Controlled-release agents using orifice, coating, and matrix - Novel amorphous solid dispersion carriers ◆Gattefosse (France) - Solubilizers for poorly soluble active pharmaceutical ingredients - Absorption enhancers for poorly permeable active pharmaceutical ingredients - Inactive lubricants 【Exhibitor Seminars】 ◆April 21 (Tuesday) 11:30-12:00, Venue 2A Release control and formulation design flexibility achieved with cellulose esters and SAIB ◆April 23 (Thursday) 11:30-12:00, Venue 2A Self-emulsifying formulation design using lipids from Gattefosse and its application to oral peptide formulations

Shima Trading Co., Ltd. will be exhibiting at the "Health Expo 2026 (44th Edition)" held at Tokyo Big Sight. This event is an exhibition where advanced products, ingredients, and technologies from the health, wellness, and beauty industries come together. Our company will be conducting a "booth exhibition" and "exhibitor presentation." It will be a great opportunity to introduce advanced ingredients and technologies, so please be sure to visit us.

Shima Trading Co., Ltd. will hold the "Scientific Seminar 2025" at the Courtyard by Marriott Tokyo Station. We will introduce the development of functional lipid-based formulations for poorly soluble and poorly absorbable active pharmaceutical ingredients. Sessions will include "Gattefosse excipients for oral formulations" and "The usefulness of novel semi-porous Janus microparticles and functional lipid additives in the oral formulation of mid-sized pharmaceuticals." A Q&A session will also be provided. We sincerely look forward to your participation.

Shima Trading Co., Ltd. will hold the "Scientific Seminar 2025" at the Senri Life Science Center. We will introduce the development of functional lipid-based formulations for poorly soluble and poorly absorbable active pharmaceutical ingredients. Sessions will include topics such as "Additives for Gattefosse Oral Formulations" and "Rheology of Self-Emulsifying Formulations." There will also be time for questions and answers. We sincerely look forward to your participation.