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Automated Patch Clamp System "QPatch II"

Benchmark system in the fields of safety pharmacology and advanced electrophysiology research!

"QPatch II" is a fully automated patch clamp system that has further evolved to meet the future demands of ion channel research while maintaining the advantages of "QPatch." It allows for easier and faster operation with reduced cell usage, obtaining proven high-quality data. The new intuitive software interface reduces human error and facilitates staff reallocation. By equipping the gripper arm with a barcode reader and adopting a plate stacking method on the workbench, we have achieved faster and more stable automation of experiments. [Features] - Rapid and robust experimental system - CiPA and cardiac safety evaluation - Optimized cell preparation - Independent control of all cells - Balancing ease of use and efficiency *For more details, please refer to the PDF materials or feel free to contact us.

Related Link - https://sophion.co.jp/products/qpatch-ll-automated…

basic information

【Other Features】 ■ Reduces human error with a simple and intuitive user interface ■ Allows direct execution of pre-set assays and re-experiments from the touch panel ■ Enables unmanned operations at night ■ Fully automated data analysis and report generation ■ Verified with nearly all commonly used ion channels ■ Capable of forming high-quality giga-ohm seals without the need for seal enhancers ■ Achieves high reproducibility ■ Highly controlled experimental environment ■ Electronic record system compliant with 21 CFR part 11 ■ System design intended for operation under GLP conditions *For more details, please refer to the PDF document or feel free to contact us.

Price range

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Applications/Examples of results

For more details, please refer to the PDF document or feel free to contact us.

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Automated Patch Clamp System "QPatch II"

PRODUCT

Voltage-gated sodium channels on QPatch AR_public14466-8

APPLICATION_NOTE

Ligand-gated ion channels - GABAA receptor pharmacology - QPatch

APPLICATION_NOTE

hCav1.2 recordings using QPatch_AR_public25267-2

APPLICATION_NOTE

Contract testing (tests for various ion channels)

PRODUCT

CHO TREx-P2X3 tested on QPatch AR_PUBLIC14580-6

APPLICATION_NOTE

CHO-Nav1.5 use-dependant blockers - QPatch AR_public15915-6

APPLICATION_NOTE

CHO & HEK-TRPM8 tested on QPatch AR_public14585-12

APPLICATION_NOTE

Characterization of P2X3 receptors using QPatch AR_public14470-2

APPLICATION_NOTE

CiPA hERG Milnes kinetic assay on QPatch AR_Public26838-1

APPLICATION_NOTE

HEK293-CaV2.2 for QPatch

APPLICATION_NOTE

Disease phenotypes in hiPSC-derived excitatory neurons - QPatch

APPLICATION_NOTE

hERG compound screening at 22°C and 35°C on QPatch II

APPLICATION_NOTE

hiPSC-CM: A robust and reproducible QPatch assay for NaV1.5

APPLICATION_NOTE

hiPSC-CM recordings using physiological solutions on QPatch

APPLICATION_NOTE

hiPSC-derived cardiomyocytes - NaV1.5 compound screening on QPatch

APPLICATION_NOTE

KV7.4 channel assay for QPatch: Biophysics and Pharmacology

APPLICATION_NOTE

Large Molecules: Wnt signal activation

APPLICATION_NOTE

IgG antibodies against α-cobratoxin as novel antivenom

APPLICATION_NOTE

QPlate Application Report_AR_public28570-3

APPLICATION_NOTE

Reduced cell consumption on QPatch/Qube with high success rates

APPLICATION_NOTE

Rescuing Automated Patch Clamp assay on low expressing cell line

APPLICATION_NOTE

CHO-hERG DUO optimized for QPatch

APPLICATION_NOTE

RD(TE671)nAchR α1 on QPatch

APPLICATION_NOTE

GH4-C1 nAchR ɑ7 - Nicotinic acetylcholine receptor ɑ7 on QPatch

APPLICATION_NOTE

CFTR channels activated by fluoride on QPatch

APPLICATION_NOTE

Fast Series Resistance Compensation on Qube 384 and QPatch

APPLICATION_NOTE

Reliable KV2.1 assays and pharmacology on the QPatch

APPLICATION_NOTE

CHO & HEK-TRPM8 tested on QPatch

APPLICATION_NOTE

CHO-hERG DUO tested on QPatch in multi-hole mode

APPLICATION_NOTE

CHO-Kv1.5 Voltage-gated potassium channels on QPatch

APPLICATION_NOTE

CHO-KvLQT1/minK on QPatch

APPLICATION_NOTE

CHO-NaV1.5 tested on QPatch

APPLICATION_NOTE

HEK293-KCa1.1 for QPatch

APPLICATION_NOTE

HEK293-TRPV1 tested on QPatch

APPLICATION_NOTE

HEK-CaV3.2 recordings on QPatch

APPLICATION_NOTE

HEK-hKir2.1 tested on QPatch

APPLICATION_NOTE

ICRAC on QPatch

APPLICATION_NOTE

NIH/3T3 Cystic fibrosis transmembrane receptors (CFTR) - QPatch

APPLICATION_NOTE

Stable response for ligand-/voltage-gated ion channels - QPatch

APPLICATION_NOTE

Ligand-gated ion channels in multi-hole mode on QPatch

APPLICATION_NOTE

Voltage/current clamp recordings of hiPSC-derived CMs on QPatch

APPLICATION_NOTE

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Distributors

Sophion Bioscience was founded by a passionate group of electrophysiologists with a common goal of providing objective patch clamp results quickly and accurately, independent of the experimenter's skill. We have grown from a small startup in Denmark to a global company, but our passion and commitment to providing high-performance patch clamp solutions remain unchanged. Through exceptional technical service and application support, we back our customers in achieving their goals. Additionally, with the continuous development of the QPatch and Qube platforms, we ensure uncompromising data quality in a user-friendly environment, from assay setup to data analysis.