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Auto Patch Clamp System "Qube384"

Make drug discovery research more efficient! Early screening with high-precision patch clamp data.

The "Qube384" is an auto patch clamp system capable of unmanned operation for over 8 hours, thanks to its unique cell maintenance and automated cell preparation mechanisms. It features a dispenser equipped with 1,536 high-precision linear motors and grippers, ensuring accuracy and speed in experiments. Additionally, it measures ion channels with high throughput and precision, facilitated by 384 independent pairs of electrodes and amplifiers. 【Features】 ■ Fully integrated system ■ Fully automated cell preparation unit ■ Sophion amplifiers essential for high-precision experiments ■ High-spec internal PC for system operation and data collection ■ Temperature control *For more details, please download the PDF or feel free to contact us.

Related Link - https://sophion.co.jp/products/qube/

basic information

【Other Features】 ■ Ergonomically designed ■ Unmanned operation at night ■ Stacker that automatically fills and dilutes solutions *For more details, please download the PDF or feel free to contact us.

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Applications/Examples of results

For more details, please download the PDF or feel free to contact us.

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Auto Patch Clamp System "Qube384"

PRODUCT

Stable Vhalf values and reliable potentiation of Kv7.3-7.2 -Qube

APPLICATION_NOTE

Pharmacological evaluation of GABAA receptor subtypes on Qube

APPLICATION_NOTE

Perforated patch clamp recordings on Qube384_AR_Public27882-2

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Large molecules: Scorpion toxin block of BK channels on Qube 384

APPLICATION_NOTE

Keep it simple – Ready-To-Use Cav1.2 cells on Qube 384

APPLICATION_NOTE

High-throughput screening for mode of action on Nav1.7 - Qube

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Electrophysiological screen of antibody-based antivenom on Qube

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High-throughput assay for Kv1.5 on Qube 384_AR_public22630-2

APPLICATION_NOTE

Electrophys characterization of hiSPC-derived motor neurons

APPLICATION_NOTE

Qube Opto384 - Optical modulation of ion channels AR_Public25880

APPLICATION_NOTE

Cav1.2 on Qube 384 Pharmacology stability and CiPA AR_Public

APPLICATION_NOTE

8-hours unattended hERG run - Qube AR_Public24211-1

APPLICATION_NOTE

CHO-KV1.3 and current clamp - Qube 384

APPLICATION_NOTE

High-throughput assay in electroporation transfected cells

APPLICATION_NOTE

Improved hiPSC CM action potential recordings on Qube 384

APPLICATION_NOTE

Interactions with GABAA receptors - primary hippocampal neurons

APPLICATION_NOTE

Intracellular messenger pathway - APC / optical stimulation

APPLICATION_NOTE

Primary brain cells on Qube 384

APPLICATION_NOTE

Stable recordings of P2X2/3 pharmacology on Qube 384

APPLICATION_NOTE

CaV1.2 on Qube 384

APPLICATION_NOTE

hCaV1.2 recordings on Qube using step, train and CiPA protocols

APPLICATION_NOTE

Fast desensitizing ion channels recorded on Qube 384

APPLICATION_NOTE

Temperature control on Qube 384 - hERG reference compounds

APPLICATION_NOTE

hiPS cell-derived CMs on Qube : Voltage/current clamp recordings

APPLICATION_NOTE

Internal solution exchange on Qube 384

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NaV1.1 currents on Qube

APPLICATION_NOTE

CHO-hNaV1.7 assay on Qube

APPLICATION_NOTE

The Intermediate Conductance Ca2+ - Activated K+ channel on Qube

APPLICATION_NOTE

TMEM16A on Qube 384

APPLICATION_NOTE

High throughput screen of antibody-based antivenom on Qube

APPLICATION_NOTE

Contract testing (tests for various ion channels)

PRODUCT

Reduced cell consumption on QPatch/Qube with high success rates

APPLICATION_NOTE

Rescuing Automated Patch Clamp assay on low expressing cell line

APPLICATION_NOTE

Fast Series Resistance Compensation on Qube 384 and QPatch

APPLICATION_NOTE

Large molecules: Scorpion toxin block of BK channels on Qube 384

APPLICATION_NOTE

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