Cysteine protease 'FabRICATOR Z (IdeZ)'
Cutting just below the hinge region of mouse IgG! There is no risk of over-digestion due to the high specificity of the enzyme!
"FabRICATOR Z (IdeZ)" is a cysteine protease that cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3, generating a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation. Some mouse IgG2a that cannot be digested by FabRICATOR can be easily digested with this product, although a longer incubation time may be required. Additionally, due to the high specificity of the enzyme, there is no risk of over-digestion. 【Features】 ■ Cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3 ■ Generates a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation ■ Some mouse IgG2a can be easily digested ■ No risk of over-digestion due to the high specificity of the enzyme *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Product Format】 ■FragIT Z: A product with enzymes immobilized on a spin column ■FabRICATOR Z: Freeze-dried enzymes ■FragIT Z kit: A set of FragIT and CaptureSelect (Fc fragment purification column) *For more details, please refer to the PDF materials or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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