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RS Liposome 3.0E NMN(1)
"RS Liposome 3.0E NMN" is a penetrating cosmetic ingredient that combines "RS Liposome 3.0," which is human stem cell culture medium "RemyStem" in liposome form, with the penetrating NMN derivative "Pentide-NMN." It is a cosmetic ingredient that doubles the penetration of functional ingredients: human stem cell culture medium processed with liposomes to enhance penetration, and a penetrating NMN derivative that induces NMN through a completely different mechanism. Furthermore, it is an ingredient that allows for the labeling of "human adipose-derived mesenchymal stem cell exosomes" by adding stem cell exosomes cultured on a separate line afterward.
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RS Liposome 3.0E Complex(3)
"RS Liposome 3.0E Complex" is a penetrating cosmetic ingredient that combines "RS Liposome 3.0," which is human stem cell culture medium "RemyStem" processed into liposomes, with the penetrating peptide vitamin C derivative "Pentide-C." It is a cosmetic ingredient that doubles the penetration of functional ingredients: human stem cell culture medium processed into liposomes to enhance penetration, and a penetrating peptide vitamin C derivative that delivers vitamin C through a completely different mechanism. In addition, it is an ingredient that allows for the labeling of "human adipose-derived mesenchymal stem cell exosomes" by adding stem cell exosomes cultured on a separate line.
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RS Liposome 3.0 Complex(1)
"RS Liposome 3.0 Complex" is a penetrating cosmetic ingredient that combines "RS Liposome 3.0," which is human stem cell culture medium "RemyStem" encapsulated in liposomes, with the penetrating peptide vitamin C derivative "Pentide-C." This cosmetic ingredient provides double penetration by combining liposome-processed human stem cell culture medium, which enhances penetration, with a penetrating peptide vitamin C derivative that delivers vitamin C through a completely different mechanism.
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RS Liposome 1.0 / 3.0 / 5.0(1)
RemyStem (human stem cell culture medium) is available in three different concentrations as a liposome-processed ingredient. This ingredient boasts enhanced stability and permeability through liposome processing. We offer three options to suit your needs and budget: "RS Liposome 3.0," a proven 30% concentration human stem cell culture medium liposome; "RS Liposome 1.0," a more affordable option with a 10% concentration of human stem cell culture medium; and "RS Liposome 5.0," for higher concentrations.
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Pentide-NMN（Penetrating NMN derivative）(2)
NMN (nicotinamide mononucleotide) is an anti-aging ingredient that is attracting attention as a supplement. However, when considered as a cosmetic ingredient, NMN (NR) is unsuitable for incorporation because it is not absorbed transdermally. 'Pentide-NMN' is an ingredient that applies penetration technology to NMN (NR), which is not absorbed transdermally. By using Pentide technology, which has the function of penetrating the stratum corneum, on an NMN (NR) derivative, the NMN derivative can be made to penetrate the skin.
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Pentide-C（Penetrating vitamin C derivative）(3)
"Pentide-C" is a vitamin C derivative stabilized by attaching a peptide to the hydroxyl group of vitamin C. What significantly differentiates it from conventional derivatives is that the attached peptide has functional properties. The peptide in "Pentide-C" penetrates the stratum corneum while remaining bound to the vitamin C. Because vitamin C and the peptide are bound by a peptide bond, this bond is hydrolyzed by peptidase. As a result, the vitamin C is easily released into a free state.
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RemyEV（Hybrid exosomes）(3)
Human stem cell culture medium is provided after being processed with liposomes to enhance its stability and permeability. "RemyEV" is a cosmetic ingredient that combines liposome-processed human stem cell culture medium with exosomes, giving it an even more advanced delivery system.
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RemyStem（Human stem cell conditioned medium）(2)
Stem cell culture is typically performed to increase the number of stem cells. Since cells require a lot of energy to increase in number, repeated cell division gradually exhausts the stem cells. On the other hand, RemyStem's stem cell culture uses a unique technique that minimizes cell number increase, and it has been confirmed that the resulting cells are rich in growth factors and protein components such as exosomes. This difference in culture method is a major characteristic of RemyStem.
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RS Mixture 9.6E(1)
Exosomes are a key component of "RemyStem." Exosomes are information capsules secreted by cells, and "RemyStem" contains approximately 10 times more exosomes compared to cultures in a typical flask. "RS Mixture 9.6E" has stem cell exosomes added after the manufacturing of "RemyStem," which are cultured on a separate line. Therefore, it can be labeled as "Human Adipose-Derived Mesenchymal Stem Cell Exosomes."
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RS Exosave（Exosome protection technology）(0)
Proteins and exosomes contained in human stem cell culture medium are known to adhere to glass and plastic, and these components are lost due to adhesion each time the container is transferred. This raw material is treated with "EXO-SAVE," an exosome protection technology that minimizes this loss. Adhesion is less likely to occur in liposome-based raw materials, and EXO-SAVE technology is used in raw materials for the undiluted solution zone. There are "RS Exosave" which uses EXO-SAVE in "RemyStem," and "RS Exosave 9.6E" which uses EXO-SAVE in "RS Mixture 9.6E."
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About the lineup(1)
As a raw material supplier of human stem cell culture medium, we offer a wide range of grades. Our raw materials are processed to enhance their penetration into the stratum corneum, and are categorized into three zones based on the degree of processing: undiluted solution zone, liposome zone, and hybrid zone.