TOC Analyzer for the Pharmaceutical Industry - Sievers M9
Rapid / Easy / Accurate TOC Measurement
The Sievers M9 can accommodate a variety of applications due to its unique gas-permeable membrane conductivity measurement method and wide measurement range (0.03 ppb to 50 ppm). Features of the Sievers M9: - No carrier gas required - Stability in ultra-low concentration range - 12 months of calibration stability - Three models to choose from based on application (laboratory type/portable type/online type) - Compliance with data integrity requirements based on 21 CFR Part 11 (optional) - The sample conductivity measurement function allows simultaneous measurement of TOC and conductivity (USP<645> Stage 1) (optional) - An auto-sampler can automatically analyze up to 63 samples (40mL) (optional)
basic information
- Total Organic Carbon (TOC) Measurement Principle: Wet UV oxidation + gas permeable membrane conductivity measurement method Measurement Range: 0.03 ppb to 50 ppm TOC Accuracy: ±2% or 0.5 ppb, whichever is greater Reproducibility: RSD less than 1% Display Digits: 3 digits Calibration Frequency: Recommended every 12 months Measurement Interval: 2 minutes Interfering Substances: Not affected by coexisting ions other than organic substances - Equipment Power Requirements: 100–240 V, 50/60 Hz, 100 VA Ambient Temperature: 5–40 °C Humidity: Up to 95% without condensation Dimensions: Varies by model Weight: Varies by model (9.8 kg to 16.2 kg) *For detailed specifications, please refer to the catalog.
Price range
Delivery Time
Model number/Brand name
Sievers M9
Applications/Examples of results
- Measurement of pharmaceutical water - Cleaning validation - TOC analysis of leachables in USP<661> (Plastic Packaging Systems and Their Components)
Detailed information
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Line up（5）
| Model number | overview |
|---|---|
| SPRD77110-01 | TOC Meter M9 Laboratory Type |
| SPRD77115-01 | TOC Meter M9 Laboratory Type (with Conductivity Measurement Function) |
| SPRD77210-01 | TOC Meter M9 Portable Type |
| SPRD77215-01 | TOC Meter M9 Portable Type (with Conductivity Measurement Function) |
| SPRD77310-01 | TOC Meter M9 Online Type |
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News about this product（2）
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Are you ready for the system suitability testing of the TOC analyzer compliant with the European Pharmacopoeia (EP 12.3) revision?
The revision of the EP that came into effect on July 1, 2026, has significantly changed the requirements for the system suitability test (SST) of TOC analyzers. After the implementation of EP 12.3, in order to clarify standardization and traceability within the EP, the standard solutions for the system suitability test of TOC analyzers must use sucrose and 1,4-benzoquinone, which are certified as EP reference substances (Chemical Reference Substances: CRS). With the EP standard solution becoming the new standard, if USP standard solutions are to be continued, it is necessary to explain the validity of adopting USP reference substances. We have published a page on our website that explains the key points of the revision, necessary responses, considerations for continuing to use USP standard solutions, and ways to utilize EP standard solutions to reduce operational burdens. If you are considering how to respond to the EP revision, please take a look at the related links. Additionally, in the related materials, we provide detailed information on the requirements for standard solutions, reference values by container type, and comparative evaluation results using Sievers TOC analyzers, highlighting key points for quality control and regulatory compliance of pharmaceutical water.
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[Notice of Exhibition Participation] Announcement of Participation in CPHI Japan 2026
~Exhibiting measurement instruments for pharmaceutical water management centered around Sievers brand products~ Central Science Co., Ltd. will exhibit at "CPhI Japan 2026 (International Pharmaceutical Development Exhibition)" held at Tokyo Big Sight from April 21 (Tuesday) to April 23 (Thursday), 2026. At this exhibition, we will focus on products from the Sievers brand and introduce various measurement instruments used for pharmaceutical water management and cleaning validation. Through the display of actual devices, you can confirm the features of the measurements and the operational image. - Main exhibited products Sievers TOC Analyzer M9 Sievers Online TOC Analyzer M500 Sievers BioBurden Rapid Measurement Device Soleil Sievers Endotoxin Analyzer Eclipse If you are interested in improving the efficiency of water quality management and quality assurance operations in the pharmaceutical and biotech fields, please stop by our booth.
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Since our establishment in 1967, we have been dedicated to the development and dissemination of water quality measurement devices that anyone can use quickly, easily, and with high precision. In today's world, where the effective use of water, a limited resource, is required alongside environmental conservation, we aim to be a total solution provider that responds to all water environments by utilizing our water quality measurement devices, technology, and services. Furthermore, leveraging the latest technology and years of know-how, we are committed to delivering user-friendly and reliable water quality measurement devices more affordably, quickly, and widely.