Swab recovery rate of the compound in the worst-case scenario (feasibility test)
[Application Note] Verification Method for Recovery Rates of TOC Method in Cases of Low Solubility Compounds or Improper Cleaning Processes
In cleaning validation, when considering worst-case scenarios involving low solubility compounds or poorly designed cleaning processes, TOC analysis is effective. TOC analysis is a non-specific analytical method that can detect substances remaining on surfaces such as APIs, surfactants, and decomposing agents.
basic information
This application note introduces a method for testing the swab recovery rate of compounds using TOC. For more details, please refer to the application note.
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Model number/Brand name
300_00005
Applications/Examples of results
Validation of cleaning for pharmaceuticals
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