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Cosmetic ingredients: Natural polysaccharide UV care material - Tanactin

UV resistance, erythema suppression, and protection against UV-induced cellular and DNA damage.

TanActine (glucomannan) is a yeast cell wall polysaccharide extracted from the culture of the yeast Candida utilis. TanActine is a yeast cell wall polysaccharide that has been shown to reduce skin redness and maintain melanin production. Data also suggests that TanActine may help in the repair of skin cells and protect against UV-induced cellular and DNA damage. <Efficacy> =In Vitro= - Promotion of melanocyte-stimulating hormone stimulation: 40% increase - Suppression of cell death due to UV irradiation - Improvement of keratinocyte cell survival rate: 10% improvement - Suppression of apoptosis: 30% suppression - DNA protective effect through inhibition of thymine dimer formation (UV irradiation): 60% suppression - Suppression of inflammatory cytokine (IL-1α) (UV irradiation): 50% suppression - Suppression of inflammatory cytokine (PGE2) (UV irradiation): 50% suppression =In Vivo= - Suppression of erythema (UV irradiation)

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basic information

TanActine (glucomannan) is a yeast cell wall polysaccharide extracted from the culture of the yeast Candida utilis. TanActine is a yeast cell wall polysaccharide that has been demonstrated to reduce skin redness and maintain melanin production. Data also suggests that TanActine may help in the repair of skin cells and protect against UV-induced cellular and DNA damage. <Efficacy> =In Vitro= - Promotion of melanocyte-stimulating hormone stimulation: 40% increase - Suppression of cell death due to UV irradiation - Improvement of keratinocyte cell survival rate: 10% increase - Suppression of apoptosis: 30% suppression - DNA protective effect through inhibition of thymine dimer formation (UV irradiation): 60% suppression - Suppression of inflammatory cytokine (IL-1α) (UV irradiation): 50% suppression - Suppression of inflammatory cytokine (PGE2) (UV irradiation): 50% suppression =In Vivo= - Suppression of erythema (UV irradiation)

Price range

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Applications/Examples of results

 Day creams 0.05 – 0.15%  Night creams 0.05 – 0.25%  Eye creams 0.02 – 0.10%  Serums 0.02 – 0.25%  Tonic 0.01 – 0.15%  Body lotions 0.15 – 0.25%  After sun lotions 0.15 – 0.25%

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.