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Cosmetic ingredient Zombie cells (aging cells) suppression Seaweed extract QT40

Zombie cells, collagen production promotion, lift-up, improvement of elasticity and firmness, dermal densification, CCNA2 gene expression, anti-aging.

Green Tech Co. confirmed the inhibitory effect on genes that protect the extracellular matrix and suppress cellular aging using a seaweed extract rich in glucuronic acid oligosaccharides against 44,000 human genes with DNA microarrays, and developed QT40. This product is a raw material that provides a lifting effect by inhibiting zombie cells and promoting extracellular matrix structural proteins. In Vitro: FGF1 gene expression stimulation: +35% CCNA2 gene expression stimulation: +80% *CCNA2 has a function that promotes cell cycle progression as a DNA repair and p21 inhibitor, and is expected to prevent cellular aging and the emergence of zombie cells. Collagen synthesis: +22% Hyaluronic acid synthesis: +17% MMP1: -29% MMP3: -31% In Vivo: Improvement of sagging: 2.8 times improvement V-line tightening: Over 60% of subjects experienced it Improvement of elasticity: +20.5%

Higuchi Trading Company - Cosmetic Ingredients Product Site (Ipros)

basic information

Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that Japanese customers perceive Green Tech as a manufacturer with a wide range of plant extracts. In fact, the company handles over 5,000 types of plant extracts. In addition to conventional plant extracts, we also produce and sell products that focus on the biodiversity of South America, particularly Brazil and the Amazon, including plant extracts and oils, as well as products developed based on microbial research that demonstrate effectiveness in maintaining microbial community stability. We also manufacture and sell products derived from algae and microalgae, including components and extracted extracts. In recent years, we have been focusing on research and development, not only enhancing the evaluation data of our products through In-Vivo and In-Vitro studies but also conducting research and development in response to new trends such as skin microbiomes. Additionally, we are committed to developing and manufacturing products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies are not only applicable to the development of our own products but also support the development of customized products.

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Applications/Examples of results

Recommended usage amount: 2.0% It is recommended to add during the cold process. ● Products that envision a V-line jaw ● Products targeting sagging and firmness ● Anti-aging products ● Products for improving skin elasticity ● Aging care products targeting zombie cells ● Aging care products for the silver generation

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.