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Cosmetic ingredient turnover-promoting enzyme protease (subtilisin)

Keratin care, turnover promotion, exfoliation promotion, smoothing the skin, wrinkle improvement, nutrient permeability promotion, anti-aging, skin regeneration, AHA alternative, powder.

This product is an enzyme refined from Bacillus subtilis using cutting-edge technology. Mechanism of Action: Skin aging leads to dysfunction between the exfoliation and adhesion mechanisms, resulting in thickening of the stratum corneum and abnormal retention of keratinocytes. The skin becomes saggy and wrinkled. By using PROTEASE (an extracellular enzyme found in the stratum corneum), peptide bonds are cleaved, inducing the dissolution of desmosomes. The processes of desquamation and cell regeneration are enhanced, slowing down skin aging. The skin's contours become smoother, and nutrient penetration is improved. Efficacy: - Improves the radiance of the complexion by stimulating the desquamation and cell turnover processes. - Smooths the skin's contours, reducing wrinkles and improving blemishes. - Promotes the penetration of nutrients. In Vitro: Approach to the stratum corneum - Adhesion improvement: +49% - Exfoliation promotion effect: +66%

Higuchi Trading Company - Cosmetic Ingredients Product Site (Ipros)

basic information

Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that Japanese customers perceive Green Tech as a manufacturer of plant extracts with a wide range of products. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, we also produce and sell products focused on the biodiversity of South America and the Amazon, such as plant extracts and oils, as well as products developed based on microbial research that demonstrate effectiveness in maintaining microbial community homeostasis. We also manufacture products derived from algae and microalgae, including components and extracted extracts. In recent years, we have been focusing on research and development, enhancing not only the evaluation data of our products in In-Vivo and In-Vitro studies but also conducting research and development in response to new trends such as skin microbiomes. Additionally, we are committed to the development and manufacturing of products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies support not only the development of our own products but also the development of customized products.

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Applications/Examples of results

Recommended addition amount: 0.1-0.5% Usage: It is recommended to use in water-free formulations. Applications: - Regenerative cosmetics - Smoothing care products - Anti-aging products - Wrinkle care products

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.