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Effect of Polylysine on the Inactivation of Microorganisms

Natural amino acid 'Polylysine' as an additive in food preservatives, hygiene materials, and daily necessities. Introducing the inactivation effect of polylisine against microorganisms.

ε-Polylysine (hereinafter referred to as Polylysine) is a substance formally known as ε-Poly-L-lysine. It is a homopolymer consisting of 25 to 35 units linked by amide bonds, formed from the ε-amino group and the α-carboxyl group of the essential amino acid L-lysine. Since 1989, it has over 30 years of manufacturing history and is widely used as a food preservative amino acid. It demonstrates inactivation effects against various microorganisms. Polylysine not only suppresses the growth of microorganisms but also has the effect of inactivating them. It similarly shows inactivation effects against enterohemorrhagic Escherichia coli O157:H7 and O111:H8. From the perspective of suppressing food spoilage, it is important to keep the initial bacterial count low, and Polylysine, which inactivates microorganisms and reduces the initial bacterial count, has excellent properties as a preservative. *For more details, please download the PDF or feel free to contact us.

Polylysine website

basic information

**Characteristics of Polylysine** - Exhibits excellent antibacterial effects against various microorganisms in small amounts. - Shows antibacterial effects over a wide pH range. - Excellent thermal stability. - Demonstrates synergistic effects when used in combination with chelating agents. - Has a rich track record of use as an additive in cosmetics, hygiene materials, and daily necessities. - Possesses excellent properties as a preservative with high safety. - Highly soluble in water, making it easy to use in food. - Exhibits excellent growth inhibition effects against a wide range of microorganisms, including Gram-positive bacteria (such as Bacillus cereus), Gram-negative bacteria (such as Escherichia coli), and yeasts, particularly those causing food poisoning. - Also shows excellent growth inhibition effects against heat-resistant bacteria, including Bacillus subtilis. - Exhibits strong inhibitory effects against lactic acid bacteria, which significantly affect food spoilage. - High safety has been confirmed through tests for acute toxicity, subacute toxicity, chronic toxicity, mutagenicity, and pharmacokinetics, in accordance with the guidelines of the Ministry of Health, Labour and Welfare. *For more details, please download the PDF or feel free to contact us.*

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Model number/Brand name

Polylysine

Applications/Examples of results

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Line up(2)

Model number overview
25% Aqueous Solution Aqueous solution containing 25% Polylysine
50% Powder Powder consisting of 50% Polylysine and 50% dextrin

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