[Data] Synergistic effects of the combination of Polylysine and chelating agents
Natural amino acid 'Polylysine' as an additive in food preservatives, hygiene materials, and daily necessities. Introducing the synergistic effect of combining Polylysine with chelating agents.
ε-Polylysine (hereinafter referred to as Polylysine) is a substance formally known as ε-Poly-L-lysine. It is a homopolymer consisting of 25 to 35 units linked by amide bonds, formed from the ε-amino group of the essential amino acid L-lysine and the α-carboxyl group. Since 1989, it has over 30 years of manufacturing history and is widely used as a food preservative amino acid. Chelating agents are commonly used in food, cosmetics, various cleaning agents, chemicals, and pharmaceuticals as metal ion sequestrants and antioxidants. It is well known that chelating agents such as EDTA and sodium citrate exhibit antibacterial properties and have been used for antibacterial purposes for a long time. We present the minimum inhibitory concentration (MIC) against Escherichia coli and Staphylococcus aureus when using Polylysine in combination with EDTA. The growth inhibition effect against each microorganism is synergistically enhanced by the combination of Polylysine and EDTA. *For more details, please download the PDF or feel free to contact us.*
basic information
**Characteristics of Polylysine** - Exhibits excellent antibacterial effects against various microorganisms in small amounts. - Shows antibacterial effects over a wide pH range. - Has excellent thermal stability. - Demonstrates synergistic effects when used in combination with chelating agents. - Has a rich track record of use as an additive in cosmetics, hygiene materials, and daily necessities. - Possesses excellent properties as a preservative with high safety. - Highly soluble in water, making it easy to use in food. - Exhibits excellent growth inhibition effects against a wide range of microorganisms, including gram-positive bacteria (such as Bacillus cereus), gram-negative bacteria (such as Escherichia coli), and yeasts, particularly food poisoning bacteria. - Also shows excellent growth inhibition effects against heat-resistant bacteria, including Bacillus subtilis. - Exhibits strong inhibitory effects against lactic acid bacteria, which significantly affect food spoilage. - High safety has been confirmed through acute toxicity, subacute toxicity, chronic toxicity, mutagenicity, and pharmacokinetic tests in accordance with the guidelines of the Ministry of Health, Labour and Welfare. *For more details, please download the PDF or feel free to contact us.*
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Model number/Brand name
Polylysine
Applications/Examples of results
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Line up（2）
| Model number | overview |
|---|---|
| 25% Aqueous Solution | Aqueous solution containing 25% Polylysine |
| 50% Powder | Powder containing 50% Polylysine and 50% dextrin |
