Reduction amino-catalyst
Synthesis of primary to tertiary amines in one pot is possible!
This is a highly active reductive amination catalyst that can synthesize primary, secondary, and tertiary amine compounds from carbonyl compounds in a one-pot reaction under mild conditions. 【Good Reactivity】 ■ High Catalytic Activity Under conditions of S/C=10,000, it is possible to synthesize 1-phenylethylamine from acetophenone. ■ High Functional Group Selectivity It can synthesize primary amines from acetophenone derivatives containing nitro or cyano groups without compromising the functional groups. ■ High Diastereoselectivity It can synthesize primary amines with high diastereoselectivity from substituted aliphatic cyclic ketones. 【Simple Reaction Operation】 ■ No Special Reaction Equipment Required Using ammonium formate or formic acid as the hydrogen source eliminates the need for special equipment such as pressure vessels. ■ Mild Reaction Conditions It can be used under reaction conditions of 60°C to reflux, making it highly practical. ■ Stable in Air This catalyst can be handled stably in air, allowing for weighing with standard laboratory equipment. For more details, please download the catalog or feel free to contact us.
basic information
Amines are useful compounds used in a wide range of fields such as pharmaceuticals, pesticides, functional materials, and resin raw materials. One of the efficient synthesis methods known is the reductive amination reaction of carbonyl compounds. At Kanto Chemical, we have developed and are selling practical reductive amination catalysts (iridium catalysts) that can synthesize primary, secondary, and tertiary amines under mild conditions, and we have received positive feedback from our customers. We offer a variety of reductive amination catalysts with different substrate applicability, so please make use of them in your product development and research.
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Applications/Examples of results
For more details, please refer to the catalog below or feel free to contact us.
