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Duloxetine hydrochloride nitrite [Ion Chromatography Technical Data]

Measurement of nitrite in duloxetine hydrochloride API by ion chromatography.

Duloxetine hydrochloride is an active pharmaceutical ingredient (API) for the treatment of depression and other neurological disorders. This technical document presents the analysis of nitrite in duloxetine hydrochloride using ion chromatography (IC) with a Metrosep A Supp 10 column equipped with direct UV/VIS detection at 215 nm.

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For sample pretreatment, we use the Metrohm Intelligent Pre-Concentration Technique with Matrix Elimination (MiPCT-ME).

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Metrom AG, based in Herisau, Switzerland, is a leading company specializing in ion analysis with over 70 years of history. It provides products and services in more than 140 countries worldwide. Based on Swiss technology developed over many years, the equipment comes with a 3-year warranty.