ForteBio On-Demand Webinar: "Efficient Antibody Screening Assays Using the Octet System for Antibody Drug and Diagnostic Development Online Basic Seminar"

ザルトリウス・ジャパン

One of the most important steps in the antibody development workflow is how to efficiently screen excellent antibodies from a large number of antibodies produced using immunological methods and phage display methods. The conventional ELISA method, which analyzes based on affinity, cannot distinguish between clones that express low-affinity antibodies at high levels and clones that express high-affinity antibodies at low levels; therefore, methods that analyze based on kinetic information become effective. The Octet system enables the identification of clones that produce high-affinity antibodies, which is considered difficult with the ELISA method. Obtaining kinetic information at an earlier stage in the development of antibody drugs and diagnostic agents can lead to the simplification of subsequent processes and accelerate the entire development flow. ■ Completed (2020/11/17) 【Update Information】 If you wish to view the webinar, please fill out your customer information from the "Details & Application" link below. After completing your application, an On-Demand viewing link will be displayed on the screen. The webinar presentation slides can be downloaded from the related catalog below.

Date and time Always open
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Related product information

Biomolecular Interaction Analysis System "Octet Systems"
High-throughput binding affinity measurement using BLI and Dip and Read assays. Accelerates kinetics analysis, quantification, and characterization.

**Application** ■ Kinetics Analysis: It is possible to measure not only affinity (binding affinity: KD) but also kinetics (association rate constant: Ka, dissociation rate constant: Kd). (Example: Screening and characterization of proteins, antibodies, nucleic acids, glycoproteins, peptides, small molecules, etc.) ■ Quantification: It is possible to quickly, easily, and at low running costs quantify protein concentrations. Complete automation of protocols significantly reduces manual tasks and achieves high-precision quantification. (Example: Screening of expression libraries, optimization of culture conditions, purification checks) ■ Characterization Analysis: Rapid examination of optimal parameters for selecting the best antibodies and constructing assay systems is possible. (Example: Epitope binning, antibody isotyping, screening of antibody pairs)