■Connecting Biomarker Discovery to Clinical Application - Explained with Real Cases of Neurodegenerative Diseases Although biomarkers are discovered, many do not reach clinical application. The reasons for this lie in multiple hurdles that arise after discovery, such as "narrowing down candidates," "reproducibility," and "connecting to clinical practice." 1. How should promising candidates obtained from comprehensive exploration be narrowed down? 2. How can reproducibility and scalability be ensured? 3. What are the key points for smoothly transitioning to clinical research? 4. What should be considered in data science throughout the overall flow? In this online seminar, we will clearly explain specific strategies for advancing from discovery to clinical application based on actual research cases of Alzheimer's disease and multiple sclerosis, in an easy-to-understand manner in Japanese. *Olink products and services are for research purposes only. Please note that they cannot be used for diagnostic purposes.

We are pleased to announce that our e-learning program on Ion Chromatography (IC) has been renewed with new content and technical information. It has been transformed into an e-learning platform that meets our customers' needs, whether they are unable to attend seminars due to distance, want to learn casually in their spare time, or wish to review foundational knowledge they feel hesitant to ask about. IC is a widely used analytical method for analyzing ionic species across various fields and is a popular analytical technique. The IC content focuses on the fundamentals of analysis and detection methods, while the IC-MS content is organized by themes specific to different fields, allowing learners to study methods and applications tailored to their objectives. It is available for free, so please take advantage of it.

This seminar will systematically explain the basics of IC device configuration, separation phenomena within the column, and the role of detectors, as well as the considerations for column selection and elution conditions in separation method design. We will also welcome Mr. Shiraishi from DNP Science Analysis Center, who will introduce specific points for utilizing IC-MS through real examples, including cases of separation and identification of amines in complex samples and approaches to cases that are difficult to address with IC alone. Furthermore, we will provide a broad explanation of examples of flow control for samples with many coexisting components and trace component analysis, key points for target ion detection, the principles of combustion ion chromatography (CIC), and the system configuration using the Thermo Scientific Cindion CIC system. This seminar aims to deepen understanding from basics to applications and organize knowledge and design concepts of IC analysis that can be applied in practice. We look forward to your attendance.

We are currently holding an on-demand seminar on food analysis aimed at ensuring food safety and improving analytical techniques. In this seminar, we will introduce practical information on the latest food analysis methods, regulatory trends, and solutions to challenges in inspection operations. Latest approaches to "food safety" using LCMS: Orbitrap Detecting off-odor components! A workflow for high-sensitivity target analysis and non-target sample comparison Methods for efficiently finding beverage aroma markers – a practical workflow for high-sensitivity non-target analysis using the Orbitrap Exploris GC mass spectrometer Utilization of charged particle detectors in food analysis and an introduction to efficient analysis using the Vanquish Duo UHPLC system Latest developments in inorganic element analysis! Systems that improve throughput and analysis examples for food and alcoholic beverages Food analysis using the Gallery discrete automatic analyzer.

This webinar will showcase the innovative impact of Olink's proteomics platform on neuroscience research and precision medicine. It will explain the advantages of large-scale protein analysis for elucidating the complex pathomechanisms of neurodegenerative diseases, early diagnosis, biomarker discovery, and accelerating drug target identification. The discussion will delve into how understanding neuroimmune interactions, brain inflammation, and regulatory pathways through proteomics technology contributes to achieving more precise and personalized healthcare. Examples of the application of Olink technology in various neurological disease fields, such as multiple sclerosis (MS), Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Parkinson's disease, will be presented, along with contributions to the development of personalized treatment strategies and improvements in diagnostic accuracy. ▶ Title: Neuroscience Research and Precision Medicine Utilizing Olink - Insights from Key Papers ▶ Speaker: Katsuhiko Sasaki (Field Application Scientist, Life Technologies Japan)

Olink Explore HT is a next-generation proteomics analysis platform that enables the high-sensitivity and high-throughput measurement of numerous proteins from small sample volumes. In this webinar, we will explain the technical features and utilization points of Olink Explore HT and the new product Reveal, based on our analysis experience using actual BioBank Japan samples. We will also introduce the differences from other platforms such as SomaScan and Illumina Protein Prep, from the perspectives of analysis design and data characteristics. This content will provide practical insights for researchers considering options for proteomics analysis in large cohort studies and biomarker discovery. Speaker: Dr. Akinori Kanai (Associate Professor, Center for Life Data Science, Graduate School of Frontier Sciences, The University of Tokyo)

Thermo Fisher Scientific will hold an online seminar focused on Extractables & Leachables (E&L). In recent years, there has been an increasing demand for single-use products in the process development and manufacturing of pharmaceuticals and vaccines. Understanding E&L from single-use bags when using these products is crucial for improving the quality of pharmaceuticals and vaccines, and it is also necessary to comprehend regulatory guidelines. This online seminar will deepen your understanding of regulatory guidelines related to E&L and teach you the key points of E&L testing based on the E&L data provided by suppliers regarding single-use products. Additionally, our specialists will introduce actual analytical methods for E&L and case studies from actual customers based on measurement data related to single-use bags. This online seminar requires prior registration (free of charge). All presentations will be conducted in Japanese. Date and Time: October 27, 2021 (Wednesday) 14:00 - 15:00 Format: Online Language: Japanese

In this online seminar, our specialists will provide an easy-to-understand introduction to various products used in CAR-T therapy development, including the newly launched human T lymphocyte proliferation medium Gibco CTS OpTmizer Pro Serum-Free Medium from January of this year, and the new closed automated cell processing system Gibco CTS Rotea System, along with applications and new information. We look forward to the participation of many individuals, from those engaged in CAR-T therapy development to those interested in regenerative medicine in general.

The RoHS Directive is a European law concerning the regulation of chemical substances in electrical and electronic equipment. It specifies a wide range of substances, from inorganic to organic materials, as regulated items and establishes respective threshold values for each. When domestic companies export products related to electrical and electronic equipment to Europe and other regions, they must demonstrate that the content of all these items is below the threshold values. This e-learning will provide an overview of GC/MS analysis related to phthalate esters in accordance with the RoHS Directive, as well as solutions for improving operational efficiency using the Thermo Scientific Chromeleon 7 chromatography data system. Additionally, the latest information on effective verification methods for the additive TOTM, which affects the false positive results for DEHP, will also be introduced.

We are currently offering an on-demand version of the highly acclaimed "30-Minute Introduction to Data Integrity!" web seminar, which was well-received in 2019. This seminar provides a clear and concise explanation of the basic terms, key points, and practical examples of data integrity in a short amount of time. If you want to learn the fundamentals of data integrity, we encourage you to watch it. You can view it at your convenience, regardless of time or location. 【Program】 Topic 1: The Basics of Data Integrity Topic 2: Practical Examples of Effective Features of the Chromeleon Chromatography Data System for Data Integrity