サーモフィッシャーサイエンティフィック株式会社/Thermo Fisher Scientific K.K. Official site

Hybrid mass spectrometer "Q Exactive Focus"

Providing the ease of use and robustness necessary for routine analysis! Equipped with multiple scanning functions!

The "Q Exactive Focus" is a hybrid mass spectrometer (MS) designed with an emphasis on operability and maintainability, combining a quadrupole and an Orbitrap (a type of Fourier transform mass spectrometer). With high resolution and mass accuracy, it enables precise qualitative analysis and also allows for quantitative analysis. Based on the proven technology of the Q Exactive, it offers excellent analytical performance and stability, making routine analysis possible across a wide range of applications. Additionally, it allows for both target screening and non-target screening in a single analysis, providing the ease of use, robustness, and functionality necessary for routine analysis. 【Features】 ■ Accurate identification with high-resolution Orbitrap ■ Covers a wide concentration range ■ Highly reliable analytical data ■ Robustness suitable for routine analysis *For more details, please refer to the PDF document or feel free to contact us. *The "Q Exactive series has been discontinued, and we now offer the more compact and robust Orbitrap Exploris series as its successor."

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basic information

**Advantages of Exploratory Pharmacokinetic Testing** - A variety of quantitative methods (full scan, SIM, PRM) can be selected according to the test. - Full scan data with high resolution and precise mass can be obtained along with MS/MS data. This allows not only the evaluation of the metabolic stability of target compounds but also the simultaneous profiling of metabolites, thereby streamlining exploratory pharmacokinetic research. - Full scan enables simultaneous quantification of multiple components. It also supports cassette incubation for protein binding tests and PAMPA, achieving further throughput improvement and cost reduction. - The SIM or PRM methods provide higher selectivity and equal or better sensitivity than triple quadrupoles, making them suitable for in vivo PK screening. *For more details, please refer to the PDF document or feel free to contact us.*

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Applications/Examples of results

For more details, please refer to the PDF document or feel free to contact us.

Hybrid mass spectrometer "Q Exactive Focus"

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Benefits of Q Exactive Focus in Exploratory Pharmacokinetic Studies

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Orbitrap Exploris 120 Mass Spectrometer Product Catalog

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