Measuring Zinc Oxide! Ion Chromatograph with Visible Absorbance Detection

Zinc oxide, which is contained in various cosmetics and pharmaceuticals/formulations, can be analyzed using ion chromatography.

◆Measurement of Zinc Oxide in Sunscreen Using Ion Chromatography with Visible Absorbance Detection◆ Sunscreens are classified as over-the-counter (OTC) drugs in the United States, and zinc oxide is one of the active ingredients that has received approval from the U.S. Food and Drug Administration (FDA) for use in sunscreens (with a maximum concentration of 25%). Zinc oxide is a powdered mineral that adheres to the outermost layer of the skin, acting as a broad-spectrum blocking agent that scatters, reflects, and absorbs ultraviolet radiation, providing protection from both UVA and UVB radiation, making it unique among sunscreen ingredients. The United States Pharmacopeia (USP) has developed monographs for FDA-approved drugs, including OTC medications, and is working to obtain the necessary information to maintain high-quality pharmaceuticals. It has also initiated a global effort to update many existing monographs across all official methods. As part of this USP initiative, the addition of an ion chromatography (IC) method for zinc measurement in General Chapter <591> is proposed. This method will serve as an alternative to the existing titration-based analytical methods in the monographs for zinc-containing pharmaceuticals. *Please download from the catalog at the bottom of the page.*

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