[Case Study] High-Sensitivity Quantitative Analysis of Volatile PFAS in Environmental Samples
Efficient PFAS analysis method using SPME Arrow fibers and Orbitrap Exploris GC.
This technical document introduces a highly sensitive quantitative analysis method for volatile perfluoroalkyl substances (PFAS) in environmental samples. By combining the Thermo Scientific Orbitrap Exploris GC high-resolution accurate mass spectrometer with Thermo Scientific SPME Arrow fibers, PFAS in complex environmental samples can be efficiently analyzed. This method allows for the detection of low concentrations of PFAS compounds with high sensitivity while minimizing sample pretreatment. Furthermore, by utilizing HRAM full scan data, both targeted compound quantification and non-target analysis can be achieved, rapidly expanding the analytical scope. In actual sample applications, PFAS compounds were detected in all samples, with particularly high concentrations confirmed in untreated wastewater and landfill leachate. 【Features】 ■ High sensitivity and high selectivity analysis through high-resolution accurate mass spectrometry ■ Efficient sample pretreatment using SPME Arrow ■ Flexible data processing with full scan data ■ Low LOD (0.1–1.4 ng/L) meets stringent reporting limits ■ Detection of a wide range of PFAS compounds in complex environmental samples
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【System Configuration】 Thermo Scientific TriPlus RSH SMART Autosampler Thermo Scientific SMART SPME Arrow 1.1 mm PDMS 100 µm Fiber Thermo Scientific TRACE 1610 GC Thermo Scientific Orbitrap Exploris GC Mass Spectrometer Thermo Scientific Chromeleon version 7.3.2 Chromatography Data System (CDS) Software Thermo Scientific Compound Discoverer Software Thermo Scientific Orbitrap GC-MS HRAM Contaminants Library
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For research use only. Not for diagnostic use. *For more details, please download the PDF or feel free to contact us.
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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.