[Case Study] High-Precision Quantification of Liposome Formulations Using HPLC CAD
HPLC CAD system for rapid and accurate analysis of liposome formulations.
The HPLC Charged Aerosol Detector (CAD) system is a solution that allows for the rapid and highly accurate quantification of lipids in liposome formulations. This technical sample presents the results of validation using the ASTM method across 12 system configurations at 4 sites (Thermo Scientific Vanquish Flex UHPLC and Vanquish Core HPLC). Reliable results were obtained across all systems, and they passed the system suitability tests. Additionally, excellent separation performance was confirmed using the Thermo Scientific Hypersil GOLD column. 【Features】 ■ High precision quantification: Quantification is possible in the range of 0.2 to 300 µg/g using linear, quadratic, and log-log calibration curves. ■ High reliability: Passed system suitability tests at all sites. ■ Excellent performance: High separation capability and rapid analysis with the Hypersil GOLD column. ■ Efficient analysis: Consistent responsiveness and high-precision results obtained quickly.
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