Olink Explore HT
Analysis platform adopted by the world's largest human proteome study, "UK Biobank-PPP."
Olink Explore HT is a next-generation multiplex proteomics analysis platform that extracts an overwhelming amount of information from small sample volumes. It can simultaneously measure over 5,400 proteins from just 2 µL of diverse samples such as plasma, serum, and CSF, achieving 99.5% high specificity and reproducibility through its unique PEA (Proximity Extension Assay) technology. By combining an automated workflow with NGS readouts, it enables high-precision and efficient analysis, accommodating a wide range of research phases from biomarker discovery to clinical research and drug development. Furthermore, it has been adopted in The UK Biobank Pharma Proteomics Project, the largest human proteome study in the world, demonstrating its performance and reliability in large-scale research projects. In addition to the installation of the equipment in laboratories, it is also available through service providers and Olink analysis services, with our staff supporting the experimental design phase according to research objectives and analysis needs.
basic information
Number of proteins: ~5,400 (validated) Sample volume: 2 µL (plasma, serum, etc.) Specificity: 99.5% (minimal cross-reactivity) Throughput: over 2000 samples/week (for one device installation) Dynamic range: fg-mg/mL, 10 logs Reading: NGS Expression value: NPX relative quantification
Price information
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Model number/Brand name
Olink Proteomics Explore HT
Applications/Examples of results
It is used for the exploration of biomarkers related to diseases and health, as well as for cohort studies. It cannot be used for diagnosis for research purposes. Examples of large-scale cohort analyses: - UKB-PPP (https://newsroom.thermofisher.com/newsroom/press-releases/press-release-details/2025/Thermo-Fisher-Scientifics-Olink-Platform-Selected-for-Worlds-Largest-Human-Proteome-Study/default.aspx) - Biobank Japan (https://biobankjp.org/) *For more details, please refer to the PDF materials or feel free to contact us.*
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Accelerating Neurodegenerative Disease Research with Proteomics Webinar | Olink Use Cases and Latest Applications
This webinar will showcase the innovative impact of Olink's proteomics platform on neuroscience research and precision medicine. It will explain the advantages of large-scale protein analysis for elucidating the complex pathomechanisms of neurodegenerative diseases, early diagnosis, biomarker discovery, and accelerating drug target identification. The discussion will delve into how understanding neuroimmune interactions, brain inflammation, and regulatory pathways through proteomics technology contributes to achieving more precise and personalized healthcare. Examples of the application of Olink technology in various neurological disease fields, such as multiple sclerosis (MS), Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Parkinson's disease, will be presented, along with contributions to the development of personalized treatment strategies and improvements in diagnostic accuracy. ▶ Title: Neuroscience Research and Precision Medicine Utilizing Olink - Insights from Key Papers ▶ Speaker: Katsuhiko Sasaki (Field Application Scientist, Life Technologies Japan)
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[On-Demand Recording] The Cutting Edge of Olink HT Analysis Supporting Large-Scale Cohort Studies
Olink Explore HT is a next-generation proteomics analysis platform that enables the high-sensitivity and high-throughput measurement of numerous proteins from small sample volumes. In this webinar, we will explain the technical features and utilization points of Olink Explore HT and the new product Reveal, based on our analysis experience using actual BioBank Japan samples. We will also introduce the differences from other platforms such as SomaScan and Illumina Protein Prep, from the perspectives of analysis design and data characteristics. This content will provide practical insights for researchers considering options for proteomics analysis in large cohort studies and biomarker discovery. Speaker: Dr. Akinori Kanai (Associate Professor, Center for Life Data Science, Graduate School of Frontier Sciences, The University of Tokyo)
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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.