Olink Target 48 Neurodegenerative Diseases
Research on neurodegenerative diseases using PEA technology, pioneering with the latest markers and absolute quantification.
Olink Target 48 Neurodegeneration is a high-performance proteomics panel specialized in neurodegenerative disease research. It can simultaneously measure 41 types of proteins, including the latest and important central nervous system biomarkers such as Aß40, Aß42, pTau217, NfL, and GFAP, which are gaining attention in Alzheimer's and Parkinson's disease research. This panel enables the acquisition of absolute quantification (ng/mL) data, which is difficult with other technologies, allowing for data comparison between studies and institutions, as well as high reproducibility in long-term longitudinal studies. With just 1µL of plasma or cerebrospinal fluid, high-sensitivity measurements can be achieved, maximizing the use of valuable clinical samples. Furthermore, by combining analyses with Olink's cytokine panel, it comprehensively captures neurodegeneration and neuroinflammation, significantly enhancing analytical power. The standardized workflow using the Signature Q100 system contributes broadly from basic research to clinical and drug discovery research.
basic information
Number of proteins: 41 (verified) Sample volume: 1 µL (plasma, serum, etc.) / panel Specificity: 99.5% (minimal cross-reactivity) Expression value: pg/mL absolute quantification Reading: quantitative PCR (Olink Signature Q100)
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Model number/Brand name
Olink Proteomics Target 48 Neurodegeneration
Applications/Examples of results
- Researchers in neurobiology, neuropathology, and biomarker studies at universities and research institutions. Involved in the translational research departments and clinical development departments of pharmaceutical and biotechnology companies. - Research utilization for the exploration of early diagnostic markers for diseases, assessment of disease progression, patient stratification, and monitoring of treatment effects. - Provides highly reproducible quantitative data, making it easy to compare between studies, and is therefore used in longitudinal studies and large cohort studies.
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Free Online Seminar: Practical Applications from Biomarker Discovery to Clinical Use
■Connecting Biomarker Discovery to Clinical Application - Explained with Real Cases of Neurodegenerative Diseases Although biomarkers are discovered, many do not reach clinical application. The reasons for this lie in multiple hurdles that arise after discovery, such as "narrowing down candidates," "reproducibility," and "connecting to clinical practice." 1. How should promising candidates obtained from comprehensive exploration be narrowed down? 2. How can reproducibility and scalability be ensured? 3. What are the key points for smoothly transitioning to clinical research? 4. What should be considered in data science throughout the overall flow? In this online seminar, we will clearly explain specific strategies for advancing from discovery to clinical application based on actual research cases of Alzheimer's disease and multiple sclerosis, in an easy-to-understand manner in Japanese. *Olink products and services are for research purposes only. Please note that they cannot be used for diagnostic purposes.
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Accelerating Neurodegenerative Disease Research with Proteomics Webinar | Olink Use Cases and Latest Applications
This webinar will showcase the innovative impact of Olink's proteomics platform on neuroscience research and precision medicine. It will explain the advantages of large-scale protein analysis for elucidating the complex pathomechanisms of neurodegenerative diseases, early diagnosis, biomarker discovery, and accelerating drug target identification. The discussion will delve into how understanding neuroimmune interactions, brain inflammation, and regulatory pathways through proteomics technology contributes to achieving more precise and personalized healthcare. Examples of the application of Olink technology in various neurological disease fields, such as multiple sclerosis (MS), Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Parkinson's disease, will be presented, along with contributions to the development of personalized treatment strategies and improvements in diagnostic accuracy. ▶ Title: Neuroscience Research and Precision Medicine Utilizing Olink - Insights from Key Papers ▶ Speaker: Katsuhiko Sasaki (Field Application Scientist, Life Technologies Japan)
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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.