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Dissolution Tester, compliant with the Japanese Pharmacopoeia, Agilent 708-DS

Corresponds to the Japanese Pharmacopoeia, USP, and EP3. The design minimizes mechanical variation factors of the device using vessels that reduce the deviation of the container's centering.

The dissolution tester 708-DS features one-touch centering with the TruAlign vessel, and its design minimizes the risk of misalignment after installation, reducing the risk of failure during mechanical calibration. It supports Japanese language, has a two-piece paddle, and significantly improves basic operability with an expanded space between the drive unit and the vessel plate. It accommodates a wide range of dosage forms for dissolution testing, including tablets, capsules, rotating cylinders, and the paddle-over-disk method.

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basic information

The precise and robust design, along with certified vessels, paddles, and baskets, supports tri-polar compatibility as well as compliance with FDA, ASTM, and JP17 reference information for mechanical calibration. The automatic tablet dispensing mechanism, automatic temperature monitoring, and automatic sampling mechanism, combined with the sampling station 850-DS, enable semi-automation of dissolution testing. Online analysis through the connection of a UV meter displays the dissolution rate in real-time. By selecting options tailored to customer applications, a wide range of device configurations from manual to automatic is possible.

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Model number/Brand name

Dissolution Tester 708-DS Agilent Technologies

Applications/Examples of results

Agilent's dissolution testers are designed to minimize the impact of external environments during dissolution testing. The results of the dissolution tests are obtained based on the formulation itself, without being influenced by the tester. The open access design allows for simpler measurements in mechanical qualification as required by the FDA and ASTM.

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