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Agilent UV-Vis Spectrophotometer Cary60

Agilent dissolution tester online UV system

The Cary 60 spectrophotometer, when combined with a pump in an online UV system, along with the sampling station 850-DS, allows for filter filtration and simultaneous sampling into test tubes or HPLC vials after filtration. **Evaluation Method for Drugs in Dissolution Testing Using Fiber Optics** Using fiber optics enables direct quantification of drugs within the vessel without the need for sampling. For example, when using fiber optics in dissolution testing for the evaluation of crystallization suppression of solid dispersions aimed at improving solubility, detailed dissolution profiles can be obtained through measurements at short intervals, as no sampling is required.

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basic information

The xenon flash lamp technology achieves a dynamic range exceeding 3.5 Abs. The lamp, with an extremely long lifespan, can be used stably for extended periods. The lamp emits light only during data reading, resulting in zero warm-up time. This minimizes the decomposition and deterioration of precious samples, as they are not excessively exposed to UV light or heat.

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Agilent Technologies

Applications/Examples of results

The combination with the Agilent Cary 60 UV-Vis spectrophotometer supports a variety of applications for dissolution testing. 【What is possible with the combination of the dissolution testing system and Cary 60】 PC control of the entire dissolution testing system (Agilent Win UV software) On-line UV dissolution testing Automatic filtration through a 0.45μm filter immediately after sampling Automatic fractionation into HPLC vials after sampling and filtration Direct absorbance measurement at the sampling position using fiber optics (optional) Compliance with 21 CFR Part 11

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