Cosmetic ingredient HyWhite (whitening sodium hyaluronate derivative)
Hyaluronic Acid Na for Whitening that Maximizes the Function of Alpha-Linolenic Acid
HyWhite is a sodium hyaluronate with whitening (brightening) properties manufactured by Contipro in the Czech Republic. HyWhite is a product that has high whitening (brightening) effects, made by partially replacing low molecular weight sodium hyaluronate with alpha-linolenic acid, which has high permeability to the skin. Alpha-linolenic acid is widely known for its strong melanin production suppression effects, and in in-vitro results, it has been confirmed to have a higher suppression effect than kojic acid. On the other hand, it is also known as a component that is difficult to formulate due to its low skin permeability and instability. This product promotes the absorption of alpha-linolenic acid, which has been a problem in the past, by replacing part of the low molecular weight hyaluronate with alpha-linolenic acid, thereby improving stability and maximizing the effects of alpha-linolenic acid. *In addition to HyWhite, Contipro also manufactures sodium hyaluronate, hydrolyzed sodium hyaluronate, and other hyaluronate derivatives.
basic information
HyWhite is a product in which low molecular weight sodium hyaluronate, highly permeable to the skin, is partially replaced with alpha-linolenic acid, resulting in a high whitening effect. Alpha-linolenic acid is widely known for its strong melanin production suppression effect, and in in vitro results, it has been confirmed to have a higher suppression effect than kojic acid. On the other hand, it has also been known as a component that is difficult to formulate due to its low skin permeability and instability. This product promotes the absorption of linolenic acid, which has been a conventional issue, by replacing a portion of low molecular weight hyaluronic acid with alpha-linolenic acid, thereby improving stability and maximizing the effects of alpha-linolenic acid. In Vitro: Melanin production: approximately 50% suppression Tyrosinase activity: approximately 40% suppression Proteasome activity: LLVY approximately 140%, LRR approximately 170%, LLE approximately 180% improvement In Vivo: Asia L value: +6.6% ITA value: +40.1% Melanin: -21.3% Number of spots: -5.6% Skin tone uniformity: 6.4% improvement Caucasus ITA: +10.6% Number of spots: -24% Number of pigmented cells: -18.6%
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Applications/Examples of results
Usage: cream, serum, lotion, face mask, etc.
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News about this product（2）
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Notice of Participation in COSME Week 2026 / 16th Cosmetics Development Exhibition
We are pleased to announce that our company will be exhibiting at COSME Week 2026, the 16th Cosmetics Development Exhibition, which will be held at Tokyo Big Sight for three days starting from January 14, 2026 (Wednesday). In this exhibition, we will introduce ingredients related to the longevity concept that are gaining attention, particularly in Europe, at the skin and cellular levels. We will showcase a variety of attractive ingredients that reflect the latest research trends, so please take this opportunity to visit our booth. We sincerely look forward to your visit.
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Report on the 10th COSME Tech 2020 Cosmetics Development Exhibition
From January 20 to 22, 2020, we exhibited at the 10th COSME Tech 2020, organized by Reed Exhibitions Japan Co., Ltd., held at Makuhari Messe. Thank you very much for visiting our booth during the event. Thanks to your support, we were able to conclude the event successfully. During the exhibition, in addition to bitop's Ectoin, we introduced products from Mirexus: ultra-high molecular weight 3D dendritic polymers, among others. If you have any questions regarding the exhibited items or the products listed in our catalogs, please feel free to reach out to us. We will respond to the inquiries received during the event in due course. We look forward to your continued support. <Product Introduced During the Event> bitop: Ectoin, Glycoin Mirexus: Ultra-high molecular weight 3D dendritic polymers Contipro: Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, New Hyaluronic Acid Derivatives Odycea: Plankton Glass Flower, Marine Bamboo, etc.
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.