In industries such as biotechnology, certification is used to ensure the calibration accuracy of flow control. Equipment that measures and controls fluid flow must be calibrated at the time of initial manufacture and then regularly recalibrated to guarantee accurate measurement and control. For measurement instrument manufacturers like Brooks Instrument, the calibration of flow measurement and control equipment using high-precision measurement systems is essential. In fact, the tightening of regulations in industries such as biotechnology places even greater demands on measurement instrument manufacturers to document known uncertainties through certification. For example, in biotechnology process systems, mass flow controllers (MFCs) control the supply of process gases such as oxygen and carbon dioxide to bioreactors. Accurately and consistently supplying these gases is one of the factors that process managers seek to verify and manage in order to maximize the yield, performance, and uptime of the bioreactor.

The research example of catalysts discussed here is the Haber-Bosch process, which produces ammonia for fertilizers on an industrial scale. The Haber-Bosch process involves reacting nitrogen and hydrogen using a metal catalyst under high temperature and pressure to produce ammonia. Research on catalysts is constantly advancing, and various catalysts have been discovered today. Initially, osmium was used as the catalyst in the Haber-Bosch process, but now iron ore is used as the catalyst. Catalyst research is conducted in pilot plants. Pilot plants provide valuable early-stage scientific data regarding reactions, material properties, and process yields, thereby reducing the technical and commercial risks associated with large-scale process plants. In this research, experiments are conducted while monitoring all parameters, including pressure, temperature, flow rate, and reaction time.

Model SLAMf50 / SLAMf51 / SLAMf53 / SLAMf60 / SLAMf61 / SLAMf63 / SLAMf64 "Durability to withstand harsh environments! Achieving excellent precision with precise mass flow control" Whether indoors or outdoors, in environments with dust or places that handle water, the 'SLAMf series' elastomer seal thermal mass flow controllers/meters provide proven high precision and long-term stability unique to the "SLA5800 family." Applications ■ Pilot plants for petrochemical and chemical gases ■ Life science bioreactors ■ Blanketing in food processing

The GP200 series is the first fully pressure-independent PMFC designed specifically for semiconductor applications. With GP200's unique differential pressure technology and state-of-the-art sensor and valve configuration, it eliminates the limitations of traditional pressure-based mass flow controllers, enabling the most extensive and accurate process gas control in the industry. Brooks developed the world's first MFC that allows for the reconfiguration of gas types and flow ranges, and has continued to refresh gas models since its release, with the same functionality incorporated into the GP200. It allows for easy reconfiguration for many gas types and a wide range of flow rates, providing flexible support for a variety of processes. The ultra-fast and highly reproducible valve control of the GP200, along with its resistance to pressure fluctuations, maintains precise flow control to the chamber even in cases of extreme supply pressure variations, enabling tighter process control. The GP200 platform supports a wide range of process conditions and can replace or upgrade many traditional pressure-based mass flow controllers.

<Published Content> Mass Flow Controllers / Mass Flow Meters Pressure Controllers Area Flow Meters Pressure and Vacuum Products Secondary Electronics & Software Communication Protocols Service & Support This is a product guide that summarizes the main features and performance in an easy-to-read format. Please make use of it.

A world where miniaturization and high performance are advancing daily. Mobile phones now have features that were unimaginable just a few years ago. The realization of such high performance is thanks to thin film technology, which is utilized in a wide range of applications as follows: 【Applications of Thin Film Technology】 - Microelectronics - Anti-reflective coatings for glass - Antibacterial metal coatings for medical devices - Flexible solar cells Thin film technology is defined as "the process of creating, coating, and processing thin film materials on a substrate surface." We are currently publishing basic knowledge materials on glass coatings for the glass industry! ⚫ Glass Coatings ⚫ What is Low-E Glass? ⚫ Laminating and Materials of Low-E Coatings ⚫ Application Requirements ⚫ What is Low-E Coating Technology? ⚫ Glass Coating Market Please take a moment to read it. https://mono.ipros.com/news/detail/129167/

Brooks has added a mass flow controller specifically designed for bioprocesses to its range of general-purpose mass flow controllers. In this article, we will introduce this product and its distinctive advantages. 1. One MFC can cover the necessary spare parts for each type of gas. 2. With a control range of 1:250, it enables high-precision and accurate flow control, reducing the number of MFCs needed. 3. It accommodates a wide range of bioreactor needs, from benchtop types to large stainless steel tanks. There is a wealth of adoption experience for both single-use and multi-use applications. For more detailed product specifications, case studies, and advantages, please feel free to contact us. A representative well-versed in flow control and bioreactors will assist you.

Hot Melt Extrusion (HME) is a method that uses heat and pressure to melt polymers and extrude them into molds in a continuous process. HME is widely applied in the plastics industry and has recently been used in pharmaceutical formulations and drug delivery systems. The HME process is used to mix active pharmaceutical ingredients (APIs) with polymers and other excipients at high temperatures and pressures. The extruded material can be cut or crushed into micro-pellets for filling into capsules or compressing into tablets. Highlights: Measurement and control of mass flow rate of supercritical CO2 Achieving accurate flow rates even at low temperatures (below -30°C) Process Solution: Due to the high reliability of Brooks Instrument's Quantim Coriolis mass flow measurement and control for fluids, systems using this mass flow can measure and control the mass flow rate of the liquid CO2 being injected, rather than the pump's operating speed. In the HME process, when CO2 is maintained above its critical temperature and critical pressure, it enters a supercritical state.

Low-emissivity (Low-E) coated architectural glass has become one of the most popular functional building materials. It plays a crucial role in improving the energy efficiency and energy-saving properties of buildings by minimizing heat loss and internal condensation. The coating (thin film) applied to the glass controls the flow of visible light energy passing through the glass. This coating alters the characteristics of light transmission, reflection, and absorption in different parts of the electromagnetic spectrum, such as infrared, visible light, and ultraviolet. When viewed from inside the building, Low-E glass reflects energy back into the building, achieving significantly lower heat loss compared to regular glass. When viewed from outside the building, Low-E glass allows the visible portion of solar energy to pass through while minimizing the infrared portion, thereby reducing heat loss from the building.

In the EtherNer/IP model, when scaling up a system built at a desktop research lab level to manufacturing level, it is relatively easy to implement specification changes from single control to recipe control. The SLA5800 series is available in a flow range from 3cc/min to a maximum of 2500L/min, allowing for scaling up by adjusting parameters to match the maximum capacity using recipes and interfaces. When replacing or adding MFCs in the evaluation system, it can be done simply with just a LAN cable and a power cable, without the need for additional hardware. This not only contributes to flexible system changes but also significantly improves space efficiency and maintainability. At the same time, IoT integration is also possible. Remote operation can be incorporated on a PC basis with a low barrier to implementation. The SLA5800 series bio package uses FDA-compliant elastomers. It is capable of providing documentation and evidence, while also increasing the shielding rate during valve closure compared to conventional products, enabling more precise adjustments of dissolved oxygen (DO) levels, particularly in oxygen control. ITW Japan Co., Ltd. Brooks Instrument

In the manufacturing process of active pharmaceutical ingredients for biopharmaceuticals, including antibody drugs and vaccines, the goal is to culture and scale up biological entities such as viruses and cells, necessitating the creation of an environment conducive to the survival of the target organisms. The research and development department continuously seeks the optimal conditions for each type of cell or virus, which involves adjusting the flow rates of air, oxygen, nitrogen, and carbon dioxide to achieve optimal concentrations. Additionally, it is crucial to maintain a stable environment by adjusting the flow rates of each gas in response to monitoring results of pH and dissolved oxygen concentration. Particularly for oxygen, even small flow rates can lead to a rapid increase in dissolved oxygen concentration, requiring precise control of the flow rates. The SLA5800 series has a proven track record in many culture devices and facilities, continuing from the previous generation 5800E/i series, and is a stable product line with a large number of units shipped and consistent maintenance continuity. ITW Japan Co., Ltd. Brooks Instrument

The importance of gas flow control and mass flow controllers in the manufacturing of biopharmaceuticals, including antibody drugs, has been frequently introduced. This time, we will introduce the applications of mass flow controllers/flow meters in medical devices. In the manufacturing and control of respiratory-related medical devices, flow meters and mass flow controllers are utilized. The key factor is to maintain the appropriate ratio of oxygen and carbon dioxide concentrations in the respiratory gas, optimizing blood concentrations. It is necessary to precisely adjust and supply the gas flow of air/oxygen. The requirements include the ability to adjust gas flow to maintain appropriate concentrations in the respiratory gas and the functionality to mix/blend. Additionally, it is important to ensure that appropriate materials are used for medical devices/equipment. For gas blending applications, we offer a range of products including area flow meters (including those with valves), the SLA5850 series mass flow controllers, and the SLA5850 Biotech package, which comes pre-installed with the required four types of gas calibration data and uses materials compliant with USP standards. ITW Japan Co., Ltd. Brooks Instrument

The SLA5800 series has passed the explosion-proof structure electrical machinery equipment type certification (domestic explosion-proof: DEK20.0062X). The products in question are as follows: ● Mass Flow Controller SLA585x series ● Mass Flow Meter SLA586x series ● Pressure Controller SLA5800 series * The pressure controller is the only product that complies with domestic explosion-proof standards. We are now ready to accept orders. For details on delivery times, prices, and specifications, please contact us at the address below or through our agents. ----------------------- Contact Information ITW Japan Co., Ltd. Brooks Instrument 1-4-4 Kitasuna, Koto-ku, Tokyo 136-0073 Phone: 03-5633-7125 Email: Sales-Japan@brooksinstrument.com

The VDM300, designed for advanced stripping and passivation processes after metal etching, achieves superior accuracy, high flow rates, a wide control range, and low power consumption compared to flash vaporization systems. Features of the VDM300: 1. Flow range: 3 slpm (DIW vapor) 2. Direct steam measurement for excellent flow accuracy 3. Direct connection to the plant's pure water supply system 4. Operable even at minimum temperature (non-heated state) 5. Optimally designed for rinsing and drainage 6. EtherCAT digital communication 7. Brooks Expert Support Tool (BEST) graphical interface

Many people may have questions like, "What can be done with IoT?" and "What is needed?" upon hearing the term IoT. Through digital communication, it is possible to obtain various information such as flow sensors, valves, circuit boards, and abnormal monitoring that were not accessible with traditional analog control. For example, by monitoring the valve opening, one can detect blockages in the equipment and identify leaks from cumulative flow. This information directly contributes to reducing downtime and improving quality through continuous long-term monitoring and knowledge-based management. Compatible models include those with digital communication via RS485, in addition to traditional analog controls like 0-5VDC and 4-20mA. (Older models such as the 58xxS, MfxxS series, SLA58xxS, and SLAMfxxS series). Even older models that do not support digital communication can be upgraded to the latest mass flow models, enabling digital communication. The dimensions between new and old models are the same, and no wiring changes are necessary. Additionally, we can provide control boxes for data collection from mass flow. This enables a "visualization" of small IoT without making large changes to the equipment.

When using a thermal mass flow meter, it is very important to understand its measurement principle. Setting high-precision and stable process conditions is not only essential but also very beneficial for troubleshooting and early detection. The sensor consists of a heater (H) placed in the center of the tube and temperature sensors (T1 and T2) positioned equidistantly on either side. The heater is continuously supplied with properly controlled power, generating heat. When there is no flow in the sensor tube, the heat from the heater is evenly transferred to temperature sensors T1 and T2, resulting in both being at the same temperature. However, when there is flow in the direction indicated by the arrows in the diagram, the fluid carries heat away from T1, causing its temperature to drop, while T2 receives heat, resulting in a temperature increase. The resulting temperature difference between T1 and T2 becomes a function of the mass flow rate of the fluid within the sensor tube. This is processed appropriately and output as an electrical signal representing the mass flow rate. (This is an excerpt from the original text.) https://www.youtube.com/watch?v=XKpX3rrt1qc [ITW Japan Co., Ltd. Brooks Instrument]

Thank you very much for your continued patronage. We apologize for the inconvenience, but we will be closed for the New Year holidays from December 28 (Saturday) to January 5 (Sunday). We will resume operations on January 6 (Monday) for the 2025 fiscal year. We appreciate your understanding.

The GF40 series is a mass flow controller/meter equipped with our proprietary MultiFlo technology. This feature allows for configuration changes to thousands of different specifications using the MultiFlo(TM) configurator (dedicated software) based on the gas type and full scale at the time of purchase. Please refer to the FloCom database for the available gas types and ranges. ▽FloCom Database (xls format file) https://cdn.brooksinstrument.com/-/media/brooks/documentation/products/accessories-and-software/software/multiflo-configurator/flocom-database-db220418---gf40-gas-listing.xls Utilize the highly accurate GF40 series, equipped with data for over 100 real gases, customized to meet your specific applications.

When measuring the flow rate of liquids or gases that are unsuitable for plastic due to high pressure or high temperature, our robust "glass tube variable area flow meter (rotameter)" allows for more accurate flow measurements. It offers a wider flow range and is suitable for various liquids and gases! 【Features】 ■ Glass tube variable area flow meter ・ Flow measurement technology with high durability, economy, and excellent operability ・ Capable of a wider flow range, suitable for various liquids and gases ■ Metal tube variable area flow meter ・ Durability and accuracy that withstands high pressure and harsh temperature environments 【Product Lineup】 ■ Glass tube variable area flow meter ・ Sho-Rate models 1350, 1355, 1358 ・ GT1600 series ■ Metal tube variable area flow meter ・ MT3750 series ・ MT3809 series ▼ For more details, visit https://www.brooksinstrument.com/ja-jp/products/variable-area-flow-meters

The manufacturing processes and various evaluation devices for secondary battery materials, biotechnology, and surface treatment, as well as flow and pressure measurement instruments used in the EPC industry, must not only meet the appropriate functions and accuracy for their applications but also possess durability that allows for safe long-term use. At ITW Japan, we offer "flow and pressure measurement instruments" such as mass flow meters/controllers and pressure controllers for gases, as well as transducers that excel in long-term stability, "Coriolis flow meters" suitable for high-precision control and measurement of small liquid flows, "metal tube area flow meters" with a wealth of experience in the EPC industry, and "glass tube area flow meters" that are highly versatile and suitable for durability and cost-effectiveness. To ensure our products are used for a long time, we provide calibration and repair maintenance not only with domestic support but also at overseas locations. 【Examples of device applications】 Solar cell-related / Semiconductor-related / Medical device-related / Centrifuges / Filtration skids / Fermentation tanks / Various coatings / Fill & finish / Bioreactors (additive supply) and more ▼ Download the materials here 　https://www.ipros.jp/product/detail/2000744379

Automate pressure control and use it as a pressure/back pressure regulator! The Auto Pressure Controller "SLA/SLAMf Series" is equipped with a wealth of options and features. By combining the SLA/SLAMf Series with mass flow controllers and meters, you can achieve consistency in control (process) with the advantages of a single platform. The SLA/SLAMf Series uses a primary flow calibration system that is traceable to international standards, characterized by high precision, long-term stability of the zero point, and excellent reproducibility based on our superior measurement systems and methods. Applications: ■ Thin film processes ■ Catalyst research and pilot processes in chemical and petrochemical industries ■ Laboratory and analytical systems ■ Fuel cell technology ■ Life sciences bioreactors

Excellent long-term stability and maintenance of production accuracy! High reliability, precision, and repeatability in measurement and control. The '5850E Series' is an elastomer-sealed thermal mass flow controller/meter. With a proven track record of active use in thousands of applications worldwide for several decades, this series is equipped with a unique stable flow sensor that provides the high reliability, precision, and repeatability in measurement and control required for today's demanding industrial production processes. 【Features】 ■ Removable flow sensor ■ No influence from installation orientation ■ Mechanical/electrical compatibility with other mass flow controllers ■ Electric valve override ■ Corrosion-resistant valve

Are you having trouble selecting repairs or alternatives for the old mass flow meters known as Legacy that you are currently using? Over the past 20 years, various manufacturers' mass flow meters have been sold in the market, many of which are still in operation today. Did you know that Brooks Instrument has consolidated the mass flow meter manufacturers that handled those devices and is providing comprehensive support for repairs and alternative product suggestions? We provide support for all mass flow meters previously sold by various manufacturers, including Tylan General, Mykrolis, Entegris, UNIT, Kinetics, and Celerity. This accounts for nearly 80% of the Legacy mass flow meters that are still actively used in today's market. In some cases, we offer repairs, while in others, we suggest replacing them with our best-selling GF series mass flow meters based on customer requests. Please feel free to consult us if you are having trouble with repairs or replacements for Legacy mass flow meters.

In recent years, processes using high-pressure gas have become increasingly active, leading to a growing demand for mass flow controllers and meters that comply with the High-Pressure Gas Safety Act. Since 2018, our company has been providing products that have passed the high-pressure gas equipment testing (KHK certification) for thermal mass flow controllers (SLA5850), primarily to the chemical and petrochemical industries, and we have built a track record of deliveries. With the recent expansion of the design pressure of our mass flow controllers to 20MPa, which can be used with cylinder pressure, we are now able to apply them to an even wider range of applications than before. What is KHK certified? KHK certified products are those that have passed the high-pressure gas equipment testing conducted by the High-Pressure Gas Safety Association (KHK), and they come with a certificate of test results for high-pressure gas equipment. Benefits of KHK certified products: High-pressure gas equipment requires administrative procedures such as permission applications, inspection applications, and notifications to the governor of the prefecture (or the mayor of the municipality). These administrative procedures involve the preparation of necessary documents and complex procedures such as equipment testing, but by simply submitting the certificate of test results for high-pressure gas equipment issued by KHK, the administrative procedures can be completed.

This is the panel material we introduced in conjunction with our participation in the H2 & FC EXPO Hydrogen Fuel Cell Exhibition (SMART ENERGY WEEK Spring). ■ New Products (Coriolis Mass Flow and High-Temperature Mass Flow) You can view it here: https://www.ipros.jp/catalog/detail/752705 It is also available from related catalogs.

The GF40 series is a mass flow controller/meter equipped with our proprietary MultiFlo technology. This feature allows for changes to be made to thousands of different specifications using the dedicated software, Brooks Expert Support Tool (BEST), based on the gas type and full scale at the time of purchase. The SLA5800 series is a model capable of providing stable flow control from low flow rates (3 sccm) to high flow rates (2500 slpm). By using our dedicated software (BEST: Brooks Expert Support Tool), customers can modify PID constants suitable for their processes and monitor various data (alarms, valve openings, etc.). This data can also be utilized for troubleshooting, contributing to the reduction of equipment downtime. ★ A paid dedicated cable is required to connect the SLA5800 series/GF40 with the dedicated software. The Brooks Expert Support Tool (BEST) can be used free of charge, except for some features.

Model 5700 "Cost-effective gas flow measurement for targeted applications" If you need a compact and economical mass flow meter that provides long-term stable flow measurement without the need for temperature or pressure adjustments, choose the 5700 series thermal mass meter. Designed with the needs of purge gas, process analysis, and analytical flow measurement in mind, it features electronic output signals as an alternative to turbine meters, area flow meters, and other volumetric flow meters, excelling in cost efficiency and stability. Applications ■ Purge gas measurement ■ Gas and humidity analyzers ■ Particle monitors ■ Medical/anesthesia oxygen systems ■ Aeration/foaming systems

The GF40 series is a mass flow controller/meter equipped with our proprietary MultiFlo technology. This feature allows for configuration changes to thousands of different specifications using the MultiFlo(TM) configurator (dedicated software) based on the gas type and full scale at the time of purchase. Please refer to the FloCom database for the available gas types and ranges. ▽FloCom database (xls format file) https://cdn.brooksinstrument.com/-/media/brooks/documentation/products/accessories-and-software/software/multiflo-configurator/flocom-database-db220418---gf40-gas-listing.xls Utilize the highly accurate GF40 series, which includes data for over 100 real gases, customized to suit your applications.

Brooks Instrument LLC, a global leader in precision fluid measurement and control technology (headquartered in Hatfield, Pennsylvania, USA, with a subsidiary in Japan under ITW Japan), has been awarded the "2022 Supplier Excellence Award" by Applied Materials, a major semiconductor manufacturing equipment manufacturer. This award recognizes companies that have demonstrated outstanding performance in areas such as quality, service, lead time reduction, on-time delivery, cost, and responsiveness. We believe it is important to build strategic relationships throughout the supply chain and will continue to strive to be a strategic partner that plays a vital role for our customers in the future. ◎ Press Release from Applied Materials Japan (translated version) https://www.appliedmaterials.com/jp/ja/news-and-media/press-releases/221214-supplier-awards-jp.html

The December issue of Japan Industrial Publishing's "Measurement Technology" introduces the product overview of the new MEMS Pirani vacuum gauge, the VersaTorr series, along with examples of its applications in advanced semiconductor processes.