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Bioreactor system for cell line development and process optimization.

■ The new features improve the performance of applications such as the following: - Clone selection - Optimization of culture media and feeds - High-density culture processes - Media exchange and passaging in cell therapy applications ■ The new variable deck reduces operator downtime and improves operator efficiency ■ The new Amber clone selection software makes the best clone decision process easier ■ The new Generation 2 liquid handler enables faster and more precise operations, capable of complex tasks such as liquid mixing and addition in multifactorial design of experiments (DoE) ■ Ambr15 is the industry-standard micro-bioreactor system used in research facilities worldwide ■ The addition of metabolite analysis equipment enables a development approach in accordance with Quality by Design (QbD) ■ Ambr15 significantly reduces the amount of culture media and consumables, thereby lowering the cost per experiment, in addition to saving on facility space, funding, and labor ■ Ambr15 contributes to better clone selection on-site, more media selection, and faster process optimization

Enhancing equipment performance that influences the success of cultivation! We have achieved improved flexibility.

【Other Features】 - Achieves a development approach based on Quality by Design - Reduces costs per experiment significantly by saving on facility space, funding, labor, as well as the amount of culture media and consumables - Enables better selection of clones on-site and more selection of culture media - Contributes to the optimization of faster processes *For more details, please refer to the PDF document or feel free to contact us.

Introducing options and accessories that can be added to the Ambr 15 Generation 2.

For more details, please refer to the PDF document or feel free to contact us.

CHO Cell Culture Optimization: A DOE Approach in the Ambr 15

For more details, please refer to the PDF document or feel free to contact us.

Industry-standard high-throughput bioreactor system optimized for process characteristic analysis.

<System Features> • An automated workstation with a built-in liquid handler capable of accommodating up to 24 single-use 250 mL culture vessels. • A continuous gas supply system that enhances process control by achieving greater similarity to larger-scale bioreactors. • Numerous analysis options, including BioPAT Viamass. • A user-friendly interface that supports strong data integrity. • An integrated camera that improves user interaction and system robustness.

A single-use benchtop bioreactor with simple operation aimed at improving productivity.

The Ambr250 modular system has both cell culture and microbial culture capabilities, making it suitable for all types of culture applications. It is characterized by its wide range of applications, including research and development of biopharmaceuticals and recombinant production. ■ Process optimization ■ Process characterization ■ Process robustness studies for QbD research ■ Process scale-down model

A fully automated bioreactor system for the development of high-density cell culture processes!

【Other Features】 ■ Dramatically improves the productivity of lab work, allowing more time to be dedicated to perfusion culture research. ■ By utilizing the built-in DoE (Design of Experiments) functionality, it is possible to reach accurate results with fewer experiments, contributing to cost reduction compared to experiments conducted in a bench-top bioreactor. ■ In perfusion culture, a wide range of important parameters such as cell density, cross-flow rate, perfusion rate, bleed volume, bleed frequency, and type of hollow fiber can be optimized. ■ Demonstrates maximum strength in research aimed at perfusion culture using single-use bag culture systems and bioreactor STR. *For more details, please refer to the PDF document or feel free to contact us.

A new bioreactor system for parallel operation of microbial culture or cell culture!

【Other Features】 ■ Excellent tool for process development ■ Rapid evaluation of extensive culture conditions and cell line/strain performance ■ Excellent scalability to large benchtop bioreactors ■ Reduction of infrastructure *For more details, please refer to the PDF document or feel free to contact us.

For protein production using CHO cell lines.

The Zaltorius CHO medium portfolio has been developed for the culture of Chinese hamster ovary (CHO) and other mammalian cell lines. CHO cells can be used for both stable expression and transient expression of recombinant proteins.

Protein characterization analysis, cell banking, safety testing services

The foundation for the approval of new biopharmaceuticals is formed by a robust analytical data package that demonstrates the safety, purity, and efficacy of the product. Sartorius's analytical testing package combines physicochemical analysis methods with biological analysis methods, providing detailed characterization tailored to each customer. Our services enable rapid data-driven decision-making during drug development using platform methods, off-the-shelf assays, and custom-developed bioassays, available from preclinical to clinical stages and lot release.