Bioreactor system "Ambr250 Perfusion"
A fully automated bioreactor system for the development of high-density cell culture processes!
The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Other Features】 ■ Dramatically improves the productivity of lab work, allowing more time to be dedicated to perfusion culture research. ■ By utilizing the built-in DoE (Design of Experiments) functionality, it is possible to reach accurate results with fewer experiments, contributing to cost reduction compared to experiments conducted in a bench-top bioreactor. ■ In perfusion culture, a wide range of important parameters such as cell density, cross-flow rate, perfusion rate, bleed volume, bleed frequency, and type of hollow fiber can be optimized. ■ Demonstrates maximum strength in research aimed at perfusion culture using single-use bag culture systems and bioreactor STR. *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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[Sending recorded video] Cutting-edge pDNA and AAV therapeutics: Comprehensive upstream process technology covering everything from process development to actual production.
Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. The development of therapeutics using viral vectors is showing strong activity, with over 30% market growth expected in the next decade. The targets for treatment are diverse, but identifying critical process parameters through process development has become an urgent issue. As the first of two webinars, we will introduce the Ambr series, a representative of process development systems in upstream processes, as well as single-use bag bioreactors up to 2000L for large-scale manufacturing, including examples of associated PAT products. *We sincerely apologize, but participation from email addresses other than those of your company or organization is not permitted. Thank you for your understanding.
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Sending recorded video: What are the equipment requirements needed for the process enhancement challenge?
Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. Since last year, Sartorius has been presenting various proposals and suitable solutions for the challenges of "enhancing processes." In this first webinar of 2022, we will delve deeper than last year's trilogy and discuss several examples regarding cost and equipment considerations. The focus will particularly be on how to manage media that significantly impacts costs and how to design equipment. Please note that this webinar will be presented as the Japanese version of the overseas webinar "Overcoming Facility Constraints Posed by Process Intensification." ▪ Method of holding: Webinar recorded broadcast [Japanese, Free]
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[Sending recorded video] 11/2 [Every Tuesday in Japan] Process Enhancement Series, all 3 sessions - Session 2: High-Throughput Bioreactor Supporting Process Enhancement Efforts
Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. The success or failure of the cultivation process significantly contributes to subsequent productivity, quality, and yield, even within the overall enhanced process. Therefore, the role of process development and optimization for cultivation is positioned as extremely important, and it is necessary to implement these approaches in conjunction with production bioreactors. As the number of considerations increases, there is a demand for cost and labor reduction, and our Amber System is the solution to achieve this. Since 2020, our model capable of perfusion cultivation has received positive feedback, and in the second installment, we will thoroughly convey this feature and its advantages. [Learnable Elements] - Evolved approaches to process development - Advantages of parallel implementation in multi-channel setups [Method of Hosting] Webinar recorded broadcast [Japanese, Free] *Special novelty items will be sent from our company to those who participated in all sessions from the first to the third on the same day.
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[Sending Recorded Video] 10/26 [Every Tuesday in Japan] Process Enhancement Series, All 3 Sessions - Session 1: Approaches to Strengthening Biopharmaceutical Manufacturing Processes
Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. In recent years, the manufacturing processes of biopharmaceuticals have been shifting from large-scale equipment structures to enhancing individual processes to increase overall production volume. The core technology continues to heavily utilize single-use systems, and various approaches are available in both upstream and downstream processes to meet the goals of drug manufacturing. We will convey how to enhance your individual processes, including approaches, solutions, and ideal states, and will delve into specific topics in subsequent sessions. [Learnable Elements] - Approaches to process enhancement - Single-use bag bioreactors - Continuous chromatography technology [Method of Delivery] Recorded broadcast [in Japanese, free of charge] *Novelty items will be sent from our company to those who participated continuously from the first to the third session on the same day.
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[On-Demand Streaming Available] 9/30 (Thursday) International Webinar "Strengthening Upstream Processes and Overcoming Challenges in Commercial Production"
Registration for this webinar has ended. Those who wish to view it on demand can register through the details and application section. In this webinar, we will explain the main features of the Amber system that correspond to various stages of clone selection under perfusion mimic conditions and complete perfusion conditions, as well as media and feed screening, and optimization of process parameters in small-scale bioreactors. [Topics] - Introduction of high-throughput capabilities for upstream intensification in various modes of Amber: perfusion mimic, ATF, TFF - Amber user case studies: showcasing performance in high-throughput enhanced process development - Discussion of a modular concept for enhanced seed trains utilizing perfusion and decision-making based on specific needs - Evaluation of time and cost advantages of modular seed trains based on predetermined process types Even if you cannot attend the live webinar, a link to the on-demand archive will be sent to those who registered.