kSep Centrifugal Separation System

Scalable single-use automated centrifugation system

The kSep system is a fully automated single-use centrifugation system that continuously concentrates, washes, and recovers supernatant or solids (cell particles). It is ideal for cell separation from fed-batch culture, high-density culture, and concentrated culture, maintaining a high cell survival rate with minimized shear stress, addressing the challenges of traditional centrifugation and filtration-based technologies.

basic information

The kSep system is a single-use system in a completely closed configuration, featuring a bowl-shaped centrifuge that does not stop rotating during discharge. It reduces contamination in downstream processes and guarantees high-quality products. With a recovery rate exceeding 97% and low shear forces, it collects pure cells. The principle of the kSep system involves maintaining a balance between centrifugal force and fluid dynamics, continuously flowing media or buffers while retaining and concentrating particles such as cells and microcarriers in a conical single-use chamber. The system can be operated under aseptic conditions, and all consumables are gamma-sterilized.

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Applications/Examples of results

- Recombinant therapy - Cell therapy (MSC, CAR-T cell, iPS, etc.) - Vaccine production - Blood processing

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Ksep system

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Single-use low shear continuous centrifugation system 'Ksep50'

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[Sending viewing URL] _Ideal for low shear stress cell recovery! Continuous centrifugation system Ksep series
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Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. The field of cell therapy and regenerative medicine is a new area that can treat diseases for which there have been no effective treatments until now. Additionally, it is expected to grow globally as an industry and has been gaining importance. In this field, it is a crucial step to recover cultured cells without damaging them and in a sterile manner. Ksep makes this step possible, which has been difficult with conventional methods. We will explain why this is possible with Ksep, comparing it to traditional methods. Furthermore, Ksep is also expected to be utilized in the field of antibody therapy. We will also explain the benefits in this area. This webinar will focus on the Ksep 50, which will be launched in 2024, and introduce the above content. Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date.

Oct 04, 2024

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Sartorius Stedim Japan K.K.

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Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.

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Sartorius Stedim Japan K.K. Official site