Single-use low shear continuous centrifugation system 'Ksep50'
Achieving a high survival rate and recovery rate.
- In the cell centrifugation process, shear forces are kept low, allowing for a seamless transition from process development (0.1 L) to GMP-compliant manufacturing (20 L). - In the closed system cell recovery process, cell processing time is reduced by 50%. - Cell recovery rate improved to over 90%. - Robust results achieved even at a cell density of up to 108 cells/mL. - Improved cell viability due to low shear counterflow separation.
basic information
Conventional centrifugation methods generate high shear forces, which often damage cells during cell processing in advanced therapies. Ksep50 employs high-performance counter-flow centrifugation, reducing shear forces to minimize cell lysis and achieve high survival and recovery rates. By utilizing this automated single-use system, manual operations are reduced, enabling a seamless scale-up from process development to commercial production while maintaining high cell survival rates and quality, all while keeping the risk of contamination low.
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Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us.
