ForteBio On-Demand Webinar "Online Seminar on Promoting Research and Development for Treatments and Vaccine Development for COVID-19 Using Octet"

ザルトリウス・ジャパン

The World Health Organization (WHO) recognized on March 11, 2020, that the novel coronavirus (COVID-19) infection had reached a pandemic level. Currently, there is a demand for the acceleration of research on treatments and vaccine development for this infection. To expedite the development of therapeutics and vaccines, advanced analytical techniques are crucial for rapid screening of many candidates and for determining the most promising candidates. The Octet system enables real-time assays of biomolecular interactions using BLI technology and allows for high-throughput screening and evaluation of candidates through simultaneous measurement of multiple samples. As a result, data from the Octet system has been featured in many papers that bring breakthroughs related to the biological research of COVID-19 and vaccine and therapeutic development. ■ Ended (2020/10/20) 【Update Information】 If you wish to view the webinar, please fill in your customer information from the "Details & Application" link below. After completing your application, an On-Demand viewing link will be displayed on the screen. The webinar presentation slides can be downloaded from the related catalog below.

Date and time Always open
Capital
Entry fee Free

Related product information

Octet application "COVID-19 Research"
We support researchers worldwide in the study and development of treatments and vaccines for SARS-CoV-2 through the Octet platform.

**Application** ■ Insights into COVID-19 Binding Epitopes (Flyer) This showcases a case where the binding mechanism of the virus was elucidated using the Octet system. ■ Rapid and High-Precision Potency Assay for Influenza Vaccines (Application Note 20) The Octet platform measures the binding of vaccines/antigens to antibodies with high throughput, accuracy, and reproducibility, providing the process development group with a robust and user-friendly measurement method as an alternative to the SRID method.
Biomolecular Interaction Analysis System "Octet Systems"
High-throughput binding affinity measurement using BLI and Dip and Read assays. Accelerates kinetics analysis, quantification, and characterization.

**Application** ■ Kinetics Analysis: It is possible to measure not only affinity (binding affinity: KD) but also kinetics (association rate constant: Ka, dissociation rate constant: Kd). (Example: Screening and characterization of proteins, antibodies, nucleic acids, glycoproteins, peptides, small molecules, etc.) ■ Quantification: It is possible to quickly, easily, and at low running costs quantify protein concentrations. Complete automation of protocols significantly reduces manual tasks and achieves high-precision quantification. (Example: Screening of expression libraries, optimization of culture conditions, purification checks) ■ Characterization Analysis: Rapid examination of optimal parameters for selecting the best antibodies and constructing assay systems is possible. (Example: Epitope binning, antibody isotyping, screening of antibody pairs)
Biomolecular Interaction Analysis System Octet N1 System
Label-free assay with just a single drop of sample. Enables simple and rapid kinetics analysis, protein quantification and detection, and assay development.

**Application** ■ Kinetics Analysis: It is possible to measure not only affinity (binding affinity: KD) but also kinetics (association rate constant: Ka, dissociation rate constant: Kd). (Example: Interaction analysis of proteins, antibodies, nucleic acids, etc.) ■ Protein Quantification: Quantification of specific protein concentrations in solutions with many contaminants, which is difficult with absorbance measurements, is possible. (Example: Protein expression monitoring, bioprocess development) ■ Protein Detection: Detection of the presence of active proteins and specific proteins in unpurified samples from just a single drop of sample is possible. (Example: Detection of specific proteins in column fractions, relative ranking of protein expression) ■ Assay Development: Rapid examination of optimal parameters for selecting the best antibodies and constructing assay systems is possible. (Example: Optimization of binding pairs, immunoassay development) *For more details, please refer to the PDF materials or feel free to contact us.*