Cysteine protease 'FabULOUS (SpeB)'
Cutting the upper part of the IgG1 hinge region! The prepared Fab fragments can be used for structural studies and more!
"FabULOUS(SpeB)" is a cysteine protease that digests the hinge regions of various species and subclasses of IgG, generating a pool of uniform Fab fragments. The prepared Fab fragments can be used for affinity studies, Fab glycosylation studies, structural studies, and more. This enzyme requires reducing conditions to show activity against IgG, and under strong reducing conditions, disulfide bonds may be reduced. 【Features】 ■ Digests the hinge regions of various species and subclasses of IgG ■ Generates a pool of uniform Fab fragments ■ The prepared Fab fragments can be used for affinity studies, Fab glycosylation studies, structural studies, and more ■ Cleaves the upper part of the IgG1 hinge region *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Product Format】 ■FabULOUS: Freeze-dried enzyme ■FabULOUS Fab kit A set of freeze-dried enzyme and CaptureSelect LC-kappa(mur) (Fab fragment purification column) *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.