SpiroKit
SpiroKit
SpiroChem has developed specially designed SPIROKITS to solve and investigate the challenges of drug discovery from hit identification to the discovery of preclinical candidates.
1～4 item / All 4 items
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SpiroKit1 pKa tunable amine
Composed of derivatives of nitrogen-containing heterocyclic compounds such as azetidine! It is possible to freely adjust the pKa.
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Switch to SpiroKit2 sp3 rich.
Solving the unique problems of sp2 carbon! Composed of sp3-rich linkers that can mimic the benzene ring structure.
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Amino acids with side chains controlled by SpiroKit3 conformation.
Composed of controlled stereochemistry amino acids! Special amino acids with β-amino acids and spiro rings as the backbone are also utilized.
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Solving and investigating drug discovery challenges: 'SpiroKit 4'
Exploration of new chemical space is possible! There are also reports of improvements in metabolic stability and ADME.
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