Genovis Inc.
Genovis Inc.
Genovis provides fast and easy-to-use proprietary enzyme tools primarily for the biopharmaceutical industry.
1～13 item / All 13 items
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Protease "OpeRATOR"
Specifically cleave proteins with O-glycans! Intermediate-level approaches using MS analysis are also possible!
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Protease 'GingisREX (RgpB)'
Specifically cleaves proteins at arginine! It also cleaves when the adjacent amino acid is proline!
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Platform technology "TransGLYCIT"
Transglycosylation of IgG! It is possible to obtain antibody preparations with specific glycoforms!
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Cysteine protease "GingisKHAN (Kgp)"
Cleavage of the upper region of the human IgG1 hinge! Produces intact and homogeneous Fab and Fc fragments.
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Cysteine protease 'FabULOUS (SpeB)'
Cutting the upper part of the IgG1 hinge region! The prepared Fab fragments can be used for structural studies and more!
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Cysteine protease 'FabRICATOR Z (IdeZ)'
Cutting just below the hinge region of mouse IgG! There is no risk of over-digestion due to the high specificity of the enzyme!
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Cysteine protease 'FabALACTICA (IgdE)'
Cutting the upper part of the human IgG1 hinge region! Research on antibodies with mutated hinge regions will also become easier!
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Cysteine protease 'FabRICATOR (IdeS)'
Cutting just below the IgG hinge region! Widely used for production monitoring and clone selection!
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Endoglycosidase (O-glycosidase) "OglyZOR"
Hydrolyze core-1O-linked glycans! The optimal activity is obtained at pH 6.5 to 7.5 and 37°C!
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Sialidase "SialEXO"
Hydrolyze sialic acid! By removing sialic acid, research on the variants inherent in proteins becomes easier!
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Beta-galactosidase "GalactEXO"
Hydrolyze β1-3,4-linked galactose! Usable for both intact glycoproteins and free oligosaccharides!
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α-N-acetylgalactosaminidase "GalNAcEXO"
Hydrolysis of α-linked GalNAc! Introducing a valuable tool to reduce sample heterogeneity!
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Affinity resin "GlycOCATCH"
Concentration of O-glycated proteins! For applications such as research on complex samples and characterization of biopharmaceuticals!
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