Cysteine protease "GingisKHAN (Kgp)"
Cleavage of the upper region of the human IgG1 hinge! Produces intact and homogeneous Fab and Fc fragments.
"GingisKHAN (Kgp)" is a cysteine protease that cleaves human IgG1 at a specific site upstream of the hinge region, producing intact and homogeneous Fab and Fc fragments. This enzyme is used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, as well as the identification of post-translational modifications. [Features] - Cleaves human IgG1 at a specific site upstream of the hinge region - Produces intact and homogeneous Fab and Fc fragments - Used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, and the identification of post-translational modifications *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Product Format】 ■GingisKHAN: Freeze-dried enzyme ■GingisKHAN Fab kit A set of freeze-dried enzyme and CaptureSelect CH1 (Fab fragment purification column) *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
