Analysis case: Evaluation of the viscoelasticity of suppositories and hair wax using a rheometer.

This is an introduction to case studies of pharmaceutical analysis by a specialist in analysis. This time, we will look at the pharmacokinetics of suppositories and the viscoelastic measurement of hair wax.

The viscoelastic measurement device, the "Discovery Hybrid Rheometer," controls the surrounding environment and performs measurements over a wide range of force, strain, and strain rate. We offer three models to meet the needs for sensitivity and capability, from the high-sensitivity HR-30 to the general-purpose HR-10. This product improves various performances and specifications, achieving accurate strain, strain rate, stress control, and normal force, and is equipped with our innovative patented Smart Swap geometry and Smart Swap temperature control system. 【Main Features】 ■ Ultra-low inertia drag cup motor (patented) ■ Magnetic bearings (patented) ■ High-resolution optical encoder ■ Optical encoder dual reader (patent pending) ■ Normal force rebalance transducer (FRT)

basic information

TA Instruments handles a viscoelastic measurement device called a "rheometer." In this article, we will introduce examples of viscoelastic measurements of familiar pharmaceutical cosmetics, specifically suppositories and hair wax, along with an easy-to-understand model of the measurement process. ◆ Softening Behavior of Suppositories in the Body For suppositories that are injected and used within the body, the viscoelasticity at storage temperature and body temperature greatly affects product performance. Therefore, we conducted temperature-dependent viscoelasticity measurements on two types of suppository samples. ◆ Application Feel of Hair Wax and Creep Recovery Test It is common to see a wide variety of hair waxes displayed, catering to different hair types and desired hairstyles. When you pick them up, each has a different feel, suggesting variations in viscoelasticity. Using a rheometer, we can quantitatively evaluate basic viscoelastic indicators such as elasticity and viscosity. Additionally, as introduced below, we can assess the stretchability and holding power of hair wax through a measurement mode that simulates the application process on hair (creep recovery test).

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Model number/Brand name

Viscoelasticity Measurement Device "Discovery DHR"

Applications/Examples of results

■ True Position Sensor (patent pending) ■ Nano Torque Motor Control ■ Excellent stress, strain, and strain rate control ■ Direct strain vibration ■ Thrust dual radial bearing design ■ Ultra-low compliance integrated molded housing ■ Heat-resistant and vibration-proof electronics design ■ Smart Swap geometry (patented) ■ Original Smart Swap temperature control system ■ Superior Peltier technology ■ Heat spreader technology (patented) ■ Active temperature control (patented) ■ Color display ■ Intuitive touch keypad ■ Traceable torque calibration (patented)