Analysis case: List of thermal analysis devices and measurement cases for bio research.
This is an introduction to analysis cases and related devices for bio research by analysis specialists. This time, we will cover three devices: ITC, TAM, and NanoDSC!
Measurement capabilities offered by TA Instruments ☆ Thermal analysis / Glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology) / Viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / Intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / Tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, etc.
basic information
At TA Instruments, we handle a wide range of equipment including "thermal analysis instruments," "viscoelastic measurement devices and rheometers," "microcalorimeters (for biological and medical fields)," and "fatigue testing machines." This time, we will introduce three types of devices known as "microcalorimeters," which are highly suitable for evaluation in the fields of biology, biotechnology, and pharmaceuticals. ◆ Isothermal Titration Calorimeter (ITC) The isothermal titration calorimeter (ITC) is a device that detects the heat changes associated with titration at a constant temperature, primarily used for analyzing molecular interactions. It measures the minute heat changes that occur when molecules bind to each other, allowing for the determination of binding ratios (n), binding constants (Ka), and changes in enthalpy of binding (ΔH) from the resulting titration curves. ◆ Isothermal Calorimeter (TAM) The thermal analysis measurement device (TAM) is a highly sensitive, stable, and flexible microcalorimeter system that can directly measure universal thermal signals, enabling quantitative thermodynamic and kinetic observations of any process. ◆ Biological Microcalorimeter (NanoDSC) The biological microcalorimeter (nano DSC) is the most widely used thermal analysis instrument for evaluating the physical properties of a broad range of materials, including polymers, pharmaceuticals, food, biological substances, organic compounds, inorganic compounds, and composite materials.
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Applications/Examples of results
Main Evaluation Items ☆ Thermal Analysis / Glass Transition, Crystallization, Thermal Decomposition Weight, Curing Reaction, Expansion Rate, Thermal Conductivity, Shrinkage Rate, Effects of Moisture, etc. ☆ Viscoelastic Measurement (Rheology) / Viscoelasticity, Elastic Modulus, Viscosity, Stress Relaxation, Creep, Master Curve, Residual Strain, Molecular Weight, Molecular Weight Distribution, etc. ☆ Calorimetry / Intermolecular Interactions, Crystallization, Amorphousness, Aggregation/Precipitation, Dispersibility, Solubility, Compatibility, Wettability, Stability, Adsorption, etc.
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*Application Closed* April Online LIVE Seminar Held! ~Battery Seminar~
On April 2nd (Friday), we will start an online seminar on batteries, inviting Mr. Yoshiyasu Saito from the National Institute of Advanced Industrial Science and Technology, Energy and Environment Division, Energy Conservation Research Department. We hope you find it useful for your research and development of batteries. Additionally, there will be a presentation from our group company, Japan Waters. We look forward to your applications. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation fee: Free Please refer to the detailed page for content and application information. We will notify you of the participation details via email one week before the event. Mr. Yoshiyasu Saito, National Institute of Advanced Industrial Science and Technology 【Title】Utilization of Thermal Measurement and Thermal Analysis in Research and Development of Lithium-Ion Batteries Others
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*Application Closed* February Online LIVE Seminar Held! ~Pharmaceutical Seminar~
★ Announcement of Online Seminar on Pharmaceuticals to be Held on February 10 ★ On February 10, we will hold a seminar on the analysis and evaluation of pharmaceuticals, featuring Dr. Kawakami from the National Institute for Materials Science (Group Leader/Chief Researcher of the Medical Application Soft Matter Group, also a Professor in the Graduate School of Pure and Applied Sciences at Tsukuba University). Additionally, there will be a presentation from our group company, Waters Japan. We look forward to your applications. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation Fee: Free Please refer to the detailed page for content and application information. We will notify you of the participation details via email one week before the event. Dr. Wataru Kawakami, National Institute for Materials Science [Title] Thermal Analysis Equipment as a Research Tool for Pharmaceuticals: Advanced Utilization Beyond Mere Evaluation Methods Others
