Pharmaceutical Analysis (Suppositories and Waxes) Rheometer
This is an introduction to case studies of pharmaceutical analysis by a specialist in analysis. This time, we will cover the pharmacokinetics of suppositories and the viscoelastic measurement of hair wax.
The viscoelastic measurement device rheometer "Discovery Hybrid Rheometer" controls the surrounding environment and performs measurements over a wide range of force, strain, and strain rate. We offer three models to meet the needs for sensitivity and capability, ranging from the high-sensitivity HR-30 to the general-purpose HR-10. This product improves various performances and specifications, achieving accurate strain, strain rate, stress control, and normal force, and is equipped with our innovative patented Smart Swap geometry and Smart Swap temperature control system. 【Main Features】 ■ Ultra-low inertia drag cup motor (patented) ■ Magnetic bearings (patented) ■ High-resolution optical encoder ■ Optical encoder dual reader (patent pending) ■ Normal force rebalance transducer (FRT)
basic information
TA Instruments handles a device called a "rheometer," which measures viscoelasticity. In this article, we will introduce examples of viscoelasticity measurements for familiar pharmaceutical cosmetics, specifically suppositories and hair wax, along with an easy-to-understand model of the measurement process. ◆ Softening Behavior of Suppositories in the Body For suppositories that are injected and used in the body, the viscoelasticity at storage temperature and body temperature significantly affects product performance. Therefore, we conducted temperature-dependent viscoelasticity measurements on two types of suppository samples. ◆ Application Feel of Hair Wax and Creep Recovery Test It is common to see a wide variety of hair waxes displayed, tailored to different hair types and desired hairstyles. When you pick them up, each has a different feel, suggesting variations in viscoelasticity. Using a rheometer, we can quantitatively evaluate basic viscoelastic indicators such as elasticity and viscosity. Additionally, as will be introduced below, we can assess the stretchability and holding power of hair wax through a measurement mode that mimics the application process on hair (creep recovery test).
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Model number/Brand name
Viscoelasticity Measurement Device "Discovery HR"
Applications/Examples of results
■ True Position Sensor (patent pending) ■ Nano Torque Motor Control ■ Excellent stress, strain, and strain rate control ■ Direct strain vibration ■ Thrust dual radial bearing design ■ Ultra-low compliance integrated molded housing ■ Heat-resistant and vibration-proof electronics design ■ Smart Swap geometry (patented) ■ Original Smart Swap temperature control system ■ Superior Peltier technology ■ Heat spreader technology (patented) ■ Active temperature control (patented) ■ Color display ■ Intuitive touch keypad ■ Traceable torque calibration (patented)
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[Title] Introduction of Accessories for Polymer Rheometers TA Instruments Application Department, Masayoshi Takano In response to the request, "I want to know more about TA's rheometer accessories!" we will introduce a wide range of accessories in two parts. The second part will mainly focus on applications for "polymers." Examples of introduced accessories: DMA, dielectric relaxation, humidity control, elongational viscosity, polymer library (Mw/MWD calculation software)
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TA Instruments Japan is a wholly-owned subsidiary of TA Instruments in Japan. We sell and provide maintenance support for thermal analysis, rheology, microcalorimeters, and mechanical analysis equipment, conduct demonstration measurements, and hold technical seminars, offering the latest information on materials and engaging in the development of measurement technologies for materials. 【Main Equipment Handled】 ☆ Thermal Analysis / Differential Scanning Calorimeter (DSC), Thermogravimetric Analyzer (TGA), Simultaneous Differential Thermal Analysis (SDT/TG-DTA), Vapor Adsorption/Desorption Analyzer (Q5000SA) ☆ Viscoelastic Measurement (Rheology) / Rotational Rheometer (DHR・ARES), Dynamic Mechanical Analyzer (RSA・DMA・EF3200), Rubber Testing Cure Meter (RPA) ☆ Microcalorimetry / Isothermal Titration Calorimeter (ITC), Microcalorimeter (NanoDSC), Isothermal Calorimeter (TAM) ☆ Thermal Property Measurement Equipment / Thermal Conductivity Meter (DTC・FOX), Thermal Diffusivity Meter (DLF, DXF), Thermal Expansion Meter (TMA, DIL), Optical Thermal Expansion Meter (ODP, HM) ☆ Fatigue Testing Machines / ElectroForce Series, BioDynamic Series