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Thermal stability testing of biopharmaceuticals using a calorimeter capable of simultaneous measurement of 24 samples.

Innovative thermal stability testing for biopharmaceuticals

The TA Instruments RS-DSC (Rapid Screening Differential Scanning Calorimeter) is a device that brings innovation to the thermal stability testing of biopharmaceuticals. The RS-DSC enables laboratories to make more informed decisions and shorten time to market through high efficiency and streamlined analysis. Features of the RS-DSC: ■ Acceleration of thermal stability testing: Analyzes up to 24 samples simultaneously, providing detailed insights quickly. It also simplifies the characterization of high-concentration pharmaceuticals. ■ Improved efficiency: Utilizes disposable MFC (microfluidic chips) to operate efficiently with samples of less than 15μl. It eliminates the hassle of sample dilution and equipment cleaning, reducing contamination risks. ■ Informed decision-making: The NanoAnalyze software processes vast amounts of data, providing detailed and accurate insights into the thermal stability and thermodynamic properties of molecules.

Related Link - https://www.tainstruments.com/rs-dsc/?lang=ja

basic information

【Specifications *Excerpt】 Cell Shape: Disposable Microfluidic Channel Cell Material: Glass Sample Format: MFC (Microfluidic Chip) Cell Volume Used: 11 µL Sample Capacity: 24 MFCs Typical Sample Concentration: 20 mg/mL – 330+ mg/mL IgG (due to protein) Sample Throughput: > 96 samples/day Temperature Range: 20–100℃ Temperature Scan Rate: 1 or 2℃/min Temperature Accuracy: ± 0.2℃ (entire calorimeter); ± 0.1℃ reproducibility

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Model number/Brand name

RS-DSC

Applications/Examples of results

Rapid Thermal Stability Screening of High Concentration Biologic Drugs Rapid Thermal Stability Screening and Selection of Monoclonal Antibody Drug Products

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Product Catalog: Multi-Sample Simultaneous Measurement Calorimeter RS-DSC (Calorimeter)

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