[Therapeutic Use] TAM IV (Calorimeter)
For the evaluation of reactions of various substances.
In the pharmaceutical industry, the study of pharmacokinetics is a crucial factor that influences the success of new drug development. Understanding the absorption, distribution, metabolism, and excretion (ADME) of drugs is essential for evaluating their efficacy and safety. In particular, it is necessary to accurately grasp the solubility, stability, and interactions of drugs. The TAM IV (calorimeter) effectively supports pharmacokinetic research by providing high sensitivity and precise temperature control to analyze the interactions between drugs and biomolecules in detail. 【Application Scenarios】 * Drug solubility testing * Analysis of drug-protein binding * Evaluation of formulation stability * Monitoring of crystallization processes 【Effects of Implementation】 * Increased efficiency in drug development * Improved quality of pharmaceuticals * Enhanced reliability of research data
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**Features** * Highest level of sensitivity and flexibility * Precise temperature control (accuracy of 0.0001°C) * Continuous measurement in real-time * Non-invasive measurement that does not destroy samples * Compatible with solids, liquids, and gases **Our Strengths** TA Instruments Japan is a leading company in the fields of thermal analysis, rheology, microcalorimetry, and mechanical analysis. With years of experience and technical expertise, we provide optimal solutions tailored to our customers' needs.
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TAM
Applications/Examples of results
Application examples Pharmaceuticals: Stability, amorphous and crystalline, adsorption Materials Chemistry: Stability, formulation testing Life Sciences: Isothermal titration, microorganisms, metabolism Chemistry: Chemical reactions
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| Model number | overview |
|---|---|
| TAMIV | Can accommodate four thermostats. |
| TAMIV 48 | A thermostat capable of holding 48 units of 4mL. |
| TAMIV XL | In addition to the XL thermostat, multiple thermostats can be installed. |
| TAM Air 3 Channel | For samples with high calorific value (can accommodate three 125mL size thermostats). |
| TAM Air 8 Channel | For samples with high calorific value (up to 8 thermostats of 20mL size can be installed). |
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TA Instruments Japan is a wholly-owned subsidiary of TA Instruments in Japan. We sell and provide maintenance support for thermal analysis, rheology, microcalorimeters, and mechanical analysis equipment, conduct demonstration measurements, and hold technical seminars, offering the latest information on materials and engaging in the development of measurement technologies for materials. 【Main Equipment Handled】 ☆ Thermal Analysis / Differential Scanning Calorimeter (DSC), Thermogravimetric Analyzer (TGA), Simultaneous Differential Thermal Analysis (SDT/TG-DTA), Vapor Adsorption/Desorption Analyzer (Q5000SA) ☆ Viscoelastic Measurement (Rheology) / Rotational Rheometer (DHR・ARES), Dynamic Mechanical Analyzer (RSA・DMA・EF3200), Rubber Testing Cure Meter (RPA) ☆ Microcalorimetry / Isothermal Titration Calorimeter (ITC), Microcalorimeter (NanoDSC), Isothermal Calorimeter (TAM) ☆ Thermal Property Measurement Equipment / Thermal Conductivity Meter (DTC・FOX), Thermal Diffusivity Meter (DLF, DXF), Thermal Expansion Meter (TMA, DIL), Optical Thermal Expansion Meter (ODP, HM) ☆ Fatigue Testing Machines / ElectroForce Series, BioDynamic Series