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Mixed-mode cation exchange solid-phase extraction column PCX series

Achieving the best mixed-mode solid-phase extraction for target compounds in LC-MS/HPLC analysis through optimal selection of reversed-phase and cation exchange.

The PCX series is a polymer-based mixed-mode solid-phase extraction column that combines reversed-phase and cation exchange. By selecting the optimal option from PSCX, HPSCX, and PWCX based on the strength of reversed-phase and the differences between strong cation/weak cation exchange, you can achieve highly selective solid-phase extraction of target toxins, drugs, or their metabolites. *For more details, please download the PDF or contact us.*

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basic information

• Three types of columns support cation exchange solid-phase extraction for various target molecules. • All three types of columns utilize a mixed-mode packing material composed of cation exchange mode and reversed-phase mode. • All three types of columns use PSDVB resin as the support material. • The HPSCX column has a stronger reversed-phase mode compared to the PSCX column, making it optimal for solid-phase extraction of highly polar target molecules. • The PWCX column is used for weak cation exchange SPE. • High adsorption capacity packing material allows for extraction concentrated to 50μl using NBE type columns/plates. • The selection of a 96-well plate type automates the process with A200.

Price information

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Delivery Time

Model number/Brand name

Resolvex Series

Applications/Examples of results

• Removal of salts and fluorescent dyes from protein and peptide samples • Purification of target molecules by reverse phase or ion exchange chromatography • Purification of plasmids and DNA • Buffer exchange before sample fractionation • SPE purification of steroids, catecholamines, TDM, DoA, vitamins, etc.

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