TSKgel HIC-ADC Butyl
Stable quality! For applications such as separation and analysis of plasmid DNA topoisomers.
"TSKgel HIC-ADC Butyl" is a hydrophobic chromatography column (HIC) that introduces butyl groups to a non-porous filler (5μm). It has high separation selectivity for antibody-drug conjugates (ADCs) and is effective for drug-antibody ratio (DAR) analysis. It enables high-resolution analysis of antibody drugs and biopharmaceuticals (10cm column) as well as rapid analysis (3.5cm column). Additionally, it offers high protein recovery rates and allows for trace analysis. Please feel free to contact us for inquiries. 【Features】 ■ High-resolution analysis of antibody drugs and biopharmaceuticals (10cm column) and rapid analysis (3.5cm column) is possible. ■ High separation selectivity for antibody-drug conjugates (ADCs) and effective for drug-antibody ratio (DAR) analysis. ■ Stable quality (low lot-to-lot variation, high durability). ■ High protein recovery rates and capability for trace analysis. *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Basic Characteristics】 ■Particle Size: 5μm ■Pore Size: Non-porous ■Ligand: Butyl Group ■pH Range: 2.0-12.0 ■Maximum Pressure Drop: 30MPa ■Maximum Flow Rate ・2.5 mL/min (3.5cm Column) ・1.5 mL/min (10cm Column) *For more details, please refer to the PDF document or feel free to contact us.
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Applications/Examples of results
【Main Target Substances and Applications】 ■ DAR analysis and purity analysis of ADCs ■ Analysis of antibody drugs, biopharmaceuticals, protein aggregates, fragment analysis, isomer separation and analysis ■ Separation and analysis of topoisomers of plasmid DNA *For more details, please refer to the PDF materials or feel free to contact us.
