Unchained Labs (アンチェインドラブズ） Official site

Accelerating formulation optimization for vaccine and pharmaceutical development.

Throughput: 10 mL/min per channel Total flow rate range: 0.1 to 30 mL/min (depending on configuration) Flow ratio (water to organic) range: 1:1 to 10:1 Standard sample volume range (when FRR is 3:1): 400 µL to 2 mL Inline dilution: Yes Standard particle size range: 40 to 200 nm (depending on formulation) PDI: Less than 0.2 (depending on formulation) Encapsulation efficiency: Over 90% (depending on formulation)

Accelerating formulation optimization for vaccine and pharmaceutical development.

Throughput: Up to 96 formulations within 6 hours Total flow range: 0.1 to 30 mL/min (depending on the tip) Flow ratio (water to organic): 1:1 to 5:1 Standard sample volume range (when FRR is 3:1): 400 µL to 2 mL Minimum input volume (including dead volume): 105 µL Continuous mode capacity range: NA Inline dilution: Yes Standard particle size range: 40 to 200 nm (depending on the formulation) PDI: Less than 0.2 (depending on the formulation) Encapsulation efficiency: Over 90% (depending on the formulation)

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Throughput: 10 samples in 15 minutes Total flow rate range: 0.1 to 30 mL/min (depending on the chip) Flow ratio (water to organic) range: 1:1 to 10:1 Standard sample volume range (when FRR is 3:1): 1 to 6.5 mL Minimum input volume (including dead volume): 320 μL Continuous mode capacity range: 20 mL to infinity in continuous mode Inline dilution: Yes Standard particle size range: 40 to 200 nm* PDI: Less than 0.2* Encapsulation efficiency: Over 90%*